Investigation of the effects of prediabetes and non - obese type 2 diabetes mellitus on the heart in experimental models

Abstract

Background and goals: Nowadays sedentary lifestyle and carbohydrate-and lipid-rich diet are huge problems worldwide. These habits can lead to the development of many pathological conditions, primarily obesity and diabetes mellitus (DM). DM is in fact a group of metabolic disorders and the main cause of the pathological changes here is hyperglycemia. This elevated blood glucose level can damage several organs, such as the heart, blood vessels, kidneys and eyes. Since cardiovascular diseases (CVD) are responsible for a significantly high proportion of death cases in the world, our research was focusing on the cardiac effects of DM. Although I.