Investigation Of The Etiological Structure And Sensitivity Of Pathogens To Antibacterial Drugs In Patients With Various Forms Of Pyelonephritis

Abstract

Introduction:Pyelonephritis is an infectious inflammatory kidney disease. One of the main directions of treatment of this disease is antibiotic therapy. But recently, due to the excessive, unjustified and inadequate use of antibiotics, the problem of antibiotic resistance of pathogens has manifested itself. In this regard , measures are being developed for the rational and effective use of antibiotics in medicine. Therefore , monitoring of resistance and updating of epidemiological data deserves special attention. Objectives: Goal: investigation of the etiological structure of pyelonephritis with the establishment of the sensitivity of pathogens to appropriate antibacterial drugs. Methods: 68 medical records with a diagnosis of pyelonephritis were analyzed Results: The most common pathogens of acute and chronic pyelonephritis were E. coli, which was isolated in 87.5±4.8% of the studied patients. Conclusions: High sensitivity of Escherichia coli to carbapenems (imepenem/cilastatin), cephalosporins (ceftriaxone, cefotaxime, cefaperazone) was determined.