Investigation of the Karnofsky Performance Status as a measure of quality of life.

Grieco, Alan; Long, Charles J.

doi:10.1037/0278-6133.3.2.129

Cited by 127 publications

(67 citation statements)

References 10 publications

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“…The major disadvantages of the KPS as a measure of HRQL are its reliance on an observer, ceiling effect, and lack of psychosocial or sexual dimensions. 20,21 The SIP measures changes in behavior caused by sickness. 22 It is broadly applicable and was designed for measuring the outcomes of care and monitoring patients' clinical progress.…”

Section: Quality Of Life After Liver Transplantationmentioning

confidence: 99%

“…The mean pretransplantation KPS score for 745 patients was 49 Ϯ 15, corresponding to a functional level described as ''disabled, requires special care and assistance.'' 20 For the 406 patients evaluated at 1 year after transplantation, the mean score was 88 Ϯ 5, corresponding to a functional level described as ''able to perform normal activities with some effort, Abbreviations: C, comparison/control group; P, includes pre-and posttransplantation data; V, used validated HRQL measure; S, reports tests of statistical significance. *Multiple studies of the same population were combined and only included once.…”

Section: Effect Sizes By Specific Hrql Instrumentmentioning

confidence: 99%

“…20 For the 216 patients evaluated more than 1 year posttransplantation, the mean score was 94 Ϯ 5, corresponding to a functional level described as ''able to perform normal activities but has minor complaints.'' 20 We calculated the percentage of change in KPS from pretransplantation to 1 year posttransplantation for the six studies that reported 1-year follow-up data, then combined these values using a random-effects model to obtain a summary effect of transplantation on Karnofsky score at 1 year. The improvement of 31.6% Ϯ 32.1% was not statistically significant (P Ն .05).…”

Section: Effect Sizes By Specific Hrql Instrumentmentioning

confidence: 99%

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Health-related quality of life after liver transplantation: A meta-analysis

et al. 1999

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The goal of this study is to assess health-related quality of life (HRQL) after orthotopic liver transplantation (OLT). Structured MEDLINE and Embase literature searches identified 5473 potentially relevant articles. Thirty-two additional references were collected from the bibliographies. Of the 5505 identified articles, 49 studies reporting data on 3576 transplant recipients met our inclusion criteria, which were an assessment of quality of life (QOL) in adult patients reported as either pretransplantation and posttransplantation data or with a comparison group and written in English. We combined posttransplantation QOL scores from 15 studies that reported data from the same QOL scales to assess the magnitude of the effect of OLT on QOL scales. We also performed a sign test on the 49 studies to evaluate the direction (positive or negative) of the effect of transplantation on QOL. Transplantation resulted in an improvement of 32% in Karnofsky scores, 11% in Sickness Impact Profile scores, and 20% to 50% in the domains of the Nottingham Health Profile. The sign test showed significant improvement in posttransplantation physical health (P F .0004), sexual functioning (P F .008), daily activities (P F .02), general HRQL (P F .02), and social functioning (P F .05), but not psychological health (P F .08). In general, the HRQL of the 3576 patients was impaired pretransplantation and improved posttransplantation. Transplant recipients reported large gains in those aspects of QOL most affected by physical health and smaller improvements in areas affected by psychological functioning.

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Section: Quality Of Life After Liver Transplantationmentioning

confidence: 99%

Section: Effect Sizes By Specific Hrql Instrumentmentioning

confidence: 99%

Section: Effect Sizes By Specific Hrql Instrumentmentioning

confidence: 99%

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Health-related quality of life after liver transplantation: A meta-analysis

et al. 1999

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“…Oncologists routinely assess patients' physical fitness using scales such as the Karnofsky (Karnofsky & Burchenal, 1949) and these have been shown to correlate well with the patient survival (Greico & Long, 1984). It would, theoretically, be desirable to extend these scales to include psychological factors such as anxiety, depression, the ability to socialise and the extent to which an individual achieves his/her expectations (Calman, 1984;Slevin, 1984).…”

mentioning

confidence: 99%

Who should measure quality of life, the doctor or the patient?

Slevin

Plant²,

Lynch³

et al. 1988

Br J Cancer

838

389

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Summary The extent to which a doctor or health professional can make a valid assessment of a patient's quality of life, anxiety and depression was investigated in a series of cancer patients. Doctors and patients filled out the same forms, viz. the Karnofsky, Spitzer, Linear Analogue Self Assessment Scales and a series of simple scales designed for this study, at the same time. Correlations between the two sets of scores were poor, suggesting that the doctors could not accurately determine what the patients felt. A further study examining the reproducibility of these scales demonstrated considerable variability in results between different doctors. It is concluded that if a reliable and consistent method of measuring quality of life in cancer patients is required, it must come from the patients themselves and not from their doctors and nurses.

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“…KPS The KPS [51] is a commonly used measure of cancer patients' functional impairment that has adequate interrater reliability, concurrent validity and discriminant validity [52]. A patient scoring under 80 on this scale is not able to achieve daily life activities.…”

Section: Questionnairesmentioning

confidence: 99%

Does psychological characteristic influence physicians’ communication styles? Impact of physicians’ locus of control on interviews with a cancer patient and a relative

Libert

Merckaert

Reynaert

et al. 2005

Support Care Cancer

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Context: Physicians' psychological characteristics may influence their communication styles and may thus interfere with patientcentred communication. Objective: Our aim was to test the hypothesis that, in interviews with a cancer patient and a relative, physicians with an "external" locus of control (LOC; who believe that life outcomes are controlled by external forces such as luck, fate or others) have a communication style different from that of physicians with an "internal" LOC (who believe that life outcomes are controlled by their own characteristics or actions). Design, setting, participants and intervention: Eighty-one voluntary physicians practising in the field of oncology were recorded while performing an actual and a simulated interview with a cancer patient and a relative. Main outcome measures: Physicians' communication skills were assessed using the Cancer Research Campaign Workshop Evaluation Manual. Physicians' LOC was assessed using the Rotter I-E scale. The communication skills of the upper and lower quartiles of physicians in respect of their scores on this scale were compared using Student's t test. Results: In actual interviews, physicians with an "external" LOC talked more to the relative (P=0.017) and used more utterances with an assessment function (P=0.010) than physicians with an "internal" LOC. In simulated interviews, physicians with an "external" LOC used less utterances that give premature information (P=0.031) and used more utterances with a supportive function, such as empathy and reassurance (P=0.029), than physicians with an "internal" LOC. Conclusion: These results provide evidence that physicians' LOC can influence their communication styles. Physicians' awareness of this influence constitutes a step towards a tailoring of their communication skills to every patient's and relative's concerns and needs and thus towards a patient-centred communication.

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Investigation of the Karnofsky Performance Status as a measure of quality of life.

Cited by 127 publications

References 10 publications

Health-related quality of life after liver transplantation: A meta-analysis

Health-related quality of life after liver transplantation: A meta-analysis

Who should measure quality of life, the doctor or the patient?

Does psychological characteristic influence physicians’ communication styles? Impact of physicians’ locus of control on interviews with a cancer patient and a relative

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