Investigation of the performance of cross-linked poly(acrylic acid) and poly(methacrylic acid) as efficient adsorbents in SPE columns for simultaneous preconcentration of tricyclic antidepressants in water samples

Tarley, César Ricardo Teixeira; Gorla, Felipe Augusto; Oliveira, Fernanda Midori de; Nascentes, Clésia C.; Ferreira, Milena do Prado; Costa, Marcello F.; Segatelli, Mariana Gava

doi:10.1039/d2ay01520j

Cited by 3 publications

(1 citation statement)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…48,49 IMH, a TCA, is a potent norepinephrine nerve terminal reuptake inhibitor, and studies confirmed the presence of such drugs in rivers and oceans and their deleterious impact on human and aquatic life. 50,51 Based on that, it is imperative to establish a rapid and accurate detection method for BPA/IMH. Recently, fluorescence detection methods have seen extensive use, due to their simple preparation process and high sensitivity.…”

Section: Introductionmentioning

confidence: 99%

Four Zn(ii)-5-(2-carboxy-phenoxy)-1,3-benzenedicarboxylate coordination polymers induced by different N-ligands: synthesis, structure, and fluorescence detection for BPA and IMH

et al. 2023

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Four Zn(ii)-5-(2-carboxy-phenoxy)-1,3-benzenedicarboxylate coordination polymers induced by different N-ligands: synthesis, structure, and fluorescence detection for BPA and IMH

et al. 2023

View full text Add to dashboard Cite

show abstract

Capabilities of a Supramolecular System Based on Hexamolybdenum Cluster Complexes in the Determination of Amitriptyline in Human Urine Using Amperometric Immunosenors

Brusnitsyn,

Medyantseva,

Ramazanova

et al. 2024

J Anal Chem

View full text Add to dashboard Cite

Possibilities of a supramolecular system based on hexamolybdenum cluster complexes in the determination of amitriptyline by amperometric immunosensors in human urine

Brusnitsyn,

Medyantseva,

Ramazanova

et al. 2024

Zhurnal Analiticheskoi Khimii

View full text Add to dashboard Cite

A method for the determination of amitriptyline as a representative of tricyclic antidepressants by immunosensors using supramolecular systems based on hexamolybdenum cluster complexes in human urine was developed. These complexes are electrochemically active and give a stable analytical signal, which was utilized in the development of amperometric immunosensors. Luminescence and dynamic light scattering methods were applied to prove the formation of a supramolecular system of self-organized hexamolybdenum nanoparticles and chitosan molecules. A composite material based on hexamolybdenum cluster complexes combined with reduced graphene oxide was developed. The working range of amitriptyline concentrations when determined by amperometric immunosensor was 1 × 10-9 -1 × 10-4 M, the lower limit of detectable contents lies at the level of 5 × 10-10 M, the content of amitriptyline in urine samples – at the level of (n – 7) × 10-8 M. Comparison of the results of the analysis by amperometric immunosensor and polarization fluorescence immunoassay showed the absence of significant systematic errors. The ability to determine amitriptyline in biological fluids makes it possible to select the optimal therapeutic dose of the drug, i.e., to develop approaches to the creation of personalized medicine.

show abstract

Investigation of the performance of cross-linked poly(acrylic acid) and poly(methacrylic acid) as efficient adsorbents in SPE columns for simultaneous preconcentration of tricyclic antidepressants in water samples

Cited by 3 publications

References 42 publications

Four Zn(ii)-5-(2-carboxy-phenoxy)-1,3-benzenedicarboxylate coordination polymers induced by different N-ligands: synthesis, structure, and fluorescence detection for BPA and IMH

Four Zn(ii)-5-(2-carboxy-phenoxy)-1,3-benzenedicarboxylate coordination polymers induced by different N-ligands: synthesis, structure, and fluorescence detection for BPA and IMH

Capabilities of a Supramolecular System Based on Hexamolybdenum Cluster Complexes in the Determination of Amitriptyline in Human Urine Using Amperometric Immunosenors

Possibilities of a supramolecular system based on hexamolybdenum cluster complexes in the determination of amitriptyline by amperometric immunosensors in human urine

Contact Info

Product

Resources

About