Investigation of the relationship between idiopathic microscopic hematuria (in the first and second trimesters) and major adverse outcomes of pregnancy

Abstract

Background:The aim of this study was to investigate the relationship between idiopathic microscopic hematuria (in the first and second trimesters) and major adverse outcomes of pregnancy.Materials and Methods:Urinalysis was done for 700 pregnant women before 24 weeks of pregnancy. Those who had 3–5 red blood cells per milliliter in urinalysis were considered positive urinalysis. Then, all individuals were examined for blood pressure and other alarm signs of pregnancy complications in each visit. All mothers were followed for the incidence of preeclampsia, preterm delivery, and pregnancy outcome until the end of pregnancy.Results:The results of this study showed that no significant difference in terms of incident of pregnancy complications between the pregnant women with and without hematuria and the only abortions and neonatal deaths differed between the two groups.Conclusion:These results suggest that further studies are needed to determine whether idiopathic microscopic hematuria can be a predictive value for pregnancy complications or not.

Pregnancy in Chronic Kidney Disease: Need for Higher Awareness. A Pragmatic Review Focused on What Could Be Improved in the Different CKD Stages and Phases

“…Addition of serum creatinine will not solve all problems, but may allow identifying at least cases with kidney function impairment. Indeed, many kidney diseases are fully asymptomatic; not all kidney diseases manifest with hypertension and proteinuria, the symptoms on which attention is more focused; haematuria or electrolyte derangements may be overlooked in pregnancy and there is a consistent overlap of signs and symptoms between PE and CKD in pregnancy [ 98 , 99 , 100 , 101 ]. These diagnostic challenges are summarised in Table 4 .…”

A simple pregnancy-related kidney disease screening method: random proteinuria testing

“…Based on their results, they advocated the use of hematuria and proteinuria as potential markers associated with pregnancy-related complications. Recently, Shahraki et al [ 8 ] reported that hematuria was associated with abortion and neonatal death, but not with other pregnancy-related complications. Thus, additional studies are needed to validate this approach.…”