Introduction Mental disorders are a primary cause of the total burden of disability and morbidity worldwide. One common mental disorder is depression, which is estimated to affect 15% of adults. 1 According to the World Health Organization (WHO), depression will become the first cause of disability-adjusted life years by 2030. 2 It is also expected that more than 350 million people will suffer from depression. 2 The Center for Disease Control and Prevention (CDC) reported that for the period 2009-2012, 7.6% of Americans aged 12 and over had depression. 3 Depression is defined as a disorder affecting the whole body and afflicting the person with mental, physical, social, and spiritual problems. 4 Depression symptoms include low mood, feelings of worthlessness, suicidal thoughts and actions, and changes in the body's natural patterns (e.g., insomnia and malnutrition). 5 Depression also negatively affects interpersonal relationships, the ability to make decisions and judge correctly, and the quality of life. 6,7 Nurses, as key members of the treatment team, experience a high level of stress daily due to the nature of their profession. 8,9 Studies have shown a significant relationship between stress and depression symptoms in nurses. Nursing is a stressful profession that can cause depression. 2 Nurses are twice as likely to suffer from depression for their professional life. 2 Some major factors which cause depression in nurses are long work shifts, fatigue, and great stress. 10 Studies have also indicated that depression makes nurses vulnerable in relationships and causes job dissatisfaction, job burnout, and early retirement. 11,12 A nurse's mental health is a crucial factor to consider in human resources retention programs. Nurses are the largest group of employees in a healthcare system, and they are exposed to a considerable level of occupational stress. 10