Investigation of the Relationship between Thalassemia and Depression to Predict a Base for Rehabilitation Measures

Abstract

This study examines the relationship between thalassemia, an inherited blood disorder, and depression, a psychologically debilitating illness. Thalassemia, which is characterized by insufficient hemoglobin production, significantly affects the quality of life and well-being of patients. As more effective treatment and even a cure for thalassemia have become possible, attention is being drawn to the assessment of depression, which is common among those affected. In addition to investigating the relationship between depression and thalassemia, this research also aims to provide a basis for patient rehabilitation. The study is conducted with a sample of 60 subjects consisting of thalassemia and non-thalassemia children aged 4 to 14 years from different areas of the province. The Beck Depression Inventory scale’s second revision has been used for this purpose. The results confirmed the hypothesis that there is a positive correlation between thalassemia and depression. Statistical analysis was performed using SPSS t-test and revealed a significant level of comorbidity with a calculated coefficient alpha of 0.768, mean of 41.40, standard deviation (SD) of 2.009, Cohen’s d of 0.188, and significance of 0.50. These results are consistent with the previous research conducted by the Iranshahr Institute (2014-2015) indicating a marked occurrence of depression in thalassemia patients. This research is needed overall to understand the relationship between mental health problems and thalassemia. However, the scope of the study is limited to a local hospital with challenges such as language barriers and cultural stigma. Despite these limitations, this study highlights the need for further research on depression in thalassemia patients and suggests avenues for future research and therapeutic rehabilitation interventions. In addition, this topic can be further researched, as diseases such as thalassemia pose great challenges in dealing with those affected. It can also help parents support the suffering child in coping with the psychological burden of the physical illness.