“…Additionally, other organ-on-a-chip models are in development, resembling the spleen, bone marrow, and lymph nodes, to gain more insight on the immune system [ 42 ]. Moreover, the development of lung-on-a-chip offers a platform for better understanding of the underlying mechanisms of pathophysiological conditions within the lungs including lung cancer, asthma, COPD, and pulmonary fibrosis [ 43 , 44 , 45 , 46 , 47 ]. Intestine-on-a-chip can recapitulate normal intestinal functions including nutrient and drug absorption, mucus secretion by intestinal epithelium, digestive capacity of gastrointestinal enzymes, and the microbial flora present in the gastrointestinal tract [ 48 , 49 ].…”