Investigation of volatiles, lipoidal matter and biological activity of the aerial parts of Dichrostachys cinerea L.

Zeid, AH Abou; Hifnawy,; Sleem, AA; Mohammed, RS

doi:10.1055/s-0029-1234412

Cited by 1 publication

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“…To synthesize AuNPs 0.1 gm of the PS was dissolved in 100 ml distilled H 2 O and the temperature was raised to 70 °C. Then, the 1 ml of Au salt solution (0.1 M) was added to the PS solution, keeping the temperature at 70 °C for 60 min with continuous stirring until developing of violet colloidal solution [34,35].…”

Section: Biosynthesis Of Monometallic Nanoparticlesmentioning

confidence: 99%

The Activity of Vossia cuspidata Polysaccharides-Derived Monometallic CuO, Ag, Au, and Trimetallic CuO-Ag-Au Nanoparticles Against Cancer, Inflammation, and Wound Healing

El-Aziz

Farahat

2023

J Inorg Organomet Polym

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The biosynthesis of metal nanoparticles using plant extracts is an eco-friendly and inexpensive solution that has strong potential and applications in science and industry. This study aims to synthesize Cu, Ag, and Au monometallic and trimetallic nanoparticles (NPs) using the extracted polysaccharides (PS) of Vossia cuspidata (Roxb.) Griff. leaves. Besides, the anti-cancer, anti-inflammatory, and wound healing potentials of the synthesized NPs were tested. The synthesized NPs were characterized using standard technological methods. We succeeded in green synthesizing CuO, Ag, Au, monometallic, and CuO-Ag-Au trimetallic NPs. The synthesized NPs had weak cytotoxicity at low concentrations (6.5 µg/ml), but the viability of cancer cells was reduced by increasing the concentration, suggesting that the synthesized NPs have potent anti-cancer properties against the cells. The synthesized NPs had 19.44–45.9 μg/ml cytotoxic activity (IC50) against the MCF-7 cell line, 16.50–51.92 μg/ml against A549, and 115.90–165.9 μg/ml for normal lung cells (WI-38). TMNPs were the most effective cytotoxic agents against all the tested cell lines, followed by AuNPs on MCF-7 and CuONPs on A549. The cotton fabric-treated TMNPs and CuONPs exhibited anti-inflammatory properties greater than fabric-treated AgNPs and AuNPs and showed the highest odema inhibition (84.61% and 79.28%, respectively). In the wound healing assay, CuONPs and TMNPs caused the highest percentages of inhibition (87.82% and 61.98%, respectively) for the wound compared to AgNPs and AuNPs. TMNPs and CuONPs were more efficient in restoring the tissue integrity of wounds than AgNPs and AuNPs. Accordingly, we recommend using TMNPs and CuONPs in the wound healing dressings.

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Section: Biosynthesis Of Monometallic Nanoparticlesmentioning

confidence: 99%