2023
DOI: 10.21203/rs.3.rs-2777242/v1
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Investigation of XPD, miR-145 and miR-770 expression in patients with end-stage renal disease

Abstract: Background: The effective maintenance of genome integrity and fidelity is vital for the normal function of our tissues and organs, and the prevention of diseases. DNA repair pathways maintain genome stability, and the adequacy of genes acting in these pathways is essential for disease suppression and direct treatment responses. Chronic kidney disease is characterized by high levels of genomic damage. In this study, we examined the expression levels of the XPDgene, which plays a role in the NER repair mechanism… Show more

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