This paper presents a numerical analysis of new airfoil, TCB6612, and compared with respect to standard airfoil NACA4412 using them in wind turbine blade. The main objective of this work is to enhance the aerodynamic performance of airfoil by changing the geometry of the airfoil in order to increase the overall power output of the wind turbine. Two software, GAMBIT and FLUENT, are used in this work; GAMBIT is used to create modeling and meshing of the airfoils while FLUENT is used to simulate and analysis the airfoils. The analysis showed that the significant enhancement in aerodynamic performance for TCB6612 is occurred. It is found that value of Cd/Cl is decreased about 10.23%, the power coefficient is reached to 51.9%, and the power output is increased about 9.8%.