Investigation on the bio-heat transfer with the dual-phase-lag effect

Liu, Kuo-Chi; Wang, Yaonan; Chen, Yuen-Shin

doi:10.1016/j.ijthermalsci.2012.02.026

Cited by 115 publications

(49 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Further study will be focus on the use of the dual-phase lagging equation as a new modified bioheat transfer equation as considered by other researchers [19,54,55,[63][64][65][66][67][68][69][70][71], where the relaxation times associated with both heat flux and the temperature gradients are considered. In particular, we have noticed that the overall tissue can be considered to be a porous medium consisting of the vascular region and the extravascular region.…”

Section: Resultsmentioning

confidence: 99%

Thermal analysis in a triple-layered skin structure with embedded vasculature, tumor, and gold nanoshells

Orndorff

Ponomarev

Dai

et al. 2017

International Journal of Heat and Mass Transfer

View full text Add to dashboard Cite

a b s t r a c tObtaining accurate temperature distributions in living tissue related to hyperthermia skin cancer treatment without using an intruding sensor is a challenge. Here, we report a mathematical model that can accurately determine the temperature distribution in the tumor region and surrounding normal tissue. The model is based on a modified Pennes' equation for the bioheat transfer in a 3-D triple-layered skin structure embedded with a vascular countercurrent network and a tumor appearing in the subcutaneous region. The vascular network is designed based on the constructal theory of multi-scale tree-shaped heat exchangers. The tumor is injected with gold nanoshells in order to be heated quickly. The proposed model is implemented numerically using a stable finite difference scheme. The method is demonstrated and tested by an example.

show abstract

Section: Resultsmentioning

confidence: 99%

Thermal analysis in a triple-layered skin structure with embedded vasculature, tumor, and gold nanoshells

Orndorff

Ponomarev

Dai

et al. 2017

International Journal of Heat and Mass Transfer

View full text Add to dashboard Cite

show abstract

“…For example, the thermal wave model generated the largest value of thermal damage at the end of heating for the epidermis-dermis interface, while the DPL model gave the smallest damage distribution along the depth of skin. Liu et al [144] applied type 1 DPL model in an 1D case and reported that the DPL model can be reduced to the Fourier model when τ t = τ T , even when the effect of blood perfusion is taken into account, as long as the thermal effect of metabolic heat generation can be neglected.…”

Section: Part 2: Numerical Studiesmentioning

confidence: 99%

Thermal injury of skin and subcutaneous tissues: A review of experimental approaches and numerical models

2017

Burns

View full text Add to dashboard Cite

Thermal injury to skin and subcutaneous tissue is common in both civilian and combat scenarios. Understanding the change in tissue morphologies and properties and the underlying mechanisms of thermal injury are of vital importance to clinical determination of the degree of burn and treatment approach. This review aims at summarizing the research involving experimental and numerical studies of skin and subcutaneous tissue subjected to thermal injury. The review consists of two parts. The first part deals with experimental studies including burn protocols and prevailing imaging approaches. The second part deals with existing numerical models for burn injuries of tissue and related computational simulations. Based on this review, we conclude that though there is literature contributing to the knowledge of the pathology and pathogenesis of tissue burn, there is scant quantitative information regarding changes in tissue properties including mechanical, thermal, electrical and optical properties as a result of burn injuries that are linked to altered tissue morphology.

show abstract

“…Vascular porous structures were designed for electrokinetic mass transfer 40 and for heat transfer in biological tissues. [41][42][43][44] Vascular designs for cooling a plate heated by a randomly moving energy beam were developed by Cetkin et al 45 Design occurs in nature not only in fluid flow systems such as river basins and human lungs but also in solid structures such as animal skeletons, 46 vegetation, 47 and bodies of vehicles. 48 Solid structures were brought under the Constructal law by the view that they are bodies shaped for the flow of stresses.…”

Section: 2mentioning

confidence: 99%

Vascular design for reducing hot spots and stresses

Rocha

Lorente

Bejan

2014

Journal of Applied Physics

View full text Add to dashboard Cite

This paper is a proposal to embed tree-shaped vasculatures in a wall designed such that the wall withstands without excessive hot spots and peak stresses the intense heating and pressure that impinge on it. The vasculature is a quilt of square-shaped panels, each panel having a tree vasculature that connects the center with the perimeter. The vascular designs for volumetric cooling can be complemented by the shaping and distributing of channels for maximum strength and thermal performance at the same time. Numerical simulations of heat flow and thermal stresses in three directions show that it is possible to determine the optimal geometric features of configurations with radial channels and trees with radial and one level of bifurcations. The global performance is evaluated in terms of the overall thermal resistance and peak von Mises stresses. The dendritic design is superior under the studied thermal condition.

show abstract

Investigation on the bio-heat transfer with the dual-phase-lag effect

Cited by 115 publications

References 30 publications

Thermal analysis in a triple-layered skin structure with embedded vasculature, tumor, and gold nanoshells

Thermal analysis in a triple-layered skin structure with embedded vasculature, tumor, and gold nanoshells

Thermal injury of skin and subcutaneous tissues: A review of experimental approaches and numerical models

Vascular design for reducing hot spots and stresses

Contact Info

Product

Resources

About