Investigation on the corrosion behavior and biocompatibility of Ti-6Al-4V implant coated with HA/TiN dual layer for medical applications

Kazemi, Maryam; Ahangarani, Shahrokh; Esmailian, Mohammad; Shanaghi, Ali

doi:10.1016/j.surfcoat.2020.126044

Cited by 65 publications

(26 citation statements)

References 60 publications

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“…The result of the pull off test reported remarkable improvement in bonding strength of HAp coating from 3 to 15 MPa after introducing the titanium boride intermediate film. In another study, Kazemi et al [ 132 ] have deposited titanium nitride (TiN) as interlayer by plasma-assisted chemical vapor deposition (PACVD) with sol-gel HAp coating on Ti alloy. Introduction of TiN layer had improved the surface roughness of the HAp coating to bone-like structure, which, in turn, promoted the apatite formation ability compared to single HAp film.…”

Section: Engineering Of the Interfacementioning

confidence: 99%

Sol-Gel Derived Hydroxyapatite Coatings for Titanium Implants: A Review

et al. 2020

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With the growing demands for bone implant therapy, titanium (Ti) and its alloys are considered as appropriate choices for the load-bearing bone implant substitutes. However, the interaction of bare Ti-based implants with the tissues is critical to the success of the implants for long-term stability. Thus, surface modifications of Ti implants with biocompatible hydroxyapatite (HAp) coatings before implantation is important and gained interest. Sol-gel is a potential technique for deposition the biocompatible HAp and has many advantages over other methods. Therefore, this review strives to provide widespread overview on the recent development of sol-gel HAp deposition on Ti. This study shows that sol-gel technique was able to produce uniform and homogenous HAp coatings and identified the role of surface pretreatment of Ti substrate, optimizing the sol-gel parameters, substitution, and reinforcement of HAp on improving the coating properties. Critical factors that influence on the characteristics of the deposited sol-gel HAp films as corrosion resistance, adhesion to substrate, bioactivity, morphological, and structural properties are discussed. The review also highlights the critical issues, the most significant challenges, and the areas requiring further research.

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Section: Engineering Of the Interfacementioning

confidence: 99%

Sol-Gel Derived Hydroxyapatite Coatings for Titanium Implants: A Review

et al. 2020

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“…In particular, the use of hydroxyapatite-based coatings is widespread [10,11], as they are close in composition to the bone mineral phase and show high bioactivity [12]. Such coatings are now clinically used for cementless arthroplasty, with partially or fully coated femoral stem [13,14].…”

Section: Introductionmentioning

confidence: 99%

Baicalein-modified hydroxyapatite nanoparticles and coatings with antibacterial and antioxidant properties

Palierse

Hélary

Krafft

et al. 2021

Materials Science and Engineering: C

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Aseptic loosening and bacterial infections are the two main causes of failure for metallic implants used for joint replacement. A coating that is both bioactive and possesses antimicrobial properties may address such shortcomings and improve the performance of the implant. We have sought to study the properties of combining hydroxyapatite-based nanoparticles or coatings with baicalein, a plant-extracted molecule with both antibacterial and antioxidant properties. (B-type) carbonated hydroxyapatite nanoparticles prepared by a chemical wet method could subsequently adsorbed by soaking in a baicalein solution. The amount of adsorbed baicalein was determined to be 63 mg.g -1 by thermogravimetric measurements. In a second approach, baicalein was adsorbed on a biomimetic calciumdeficient hydroxyapatite planar coating (12 m thick) deposited on Ti6Al4V alloy from an aqueous solution of calcium, phosphate, sodium and magnesium salts. Soaking of the hydroxyapatite coated on titanium alloy in a baicalein solution induced partial dissolution/remodeling of the upper surface of the coating. However, the observed remodeling of the surface was much more pronounced in the presence of a baicalein solution, compared to pure water. The presence of adsorbed baicalein on the HAp layer, although it could not be precisely quantified, was assessed by XPS and fluorescence analysis. Planar coatings exhibited significant antibacterial properties against Staphylococcus epidermidis. Baicaleinmodified nanoparticles exhibited significant antioxidant properties. These results illustrate the potential of hydroxyapatite used as a carrier for natural biologically-active molecules and also discuss the challenges associated with their applications as antibacterial agents.

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“…The surface state reflects the surface qualities and properties of alloying layers, which affect the corrosion resistance and biocompatibility. The change in the surface roughness of the Nb-Zr alloying layer will affect the surface properties, corrosion resistance, and biocompatibility of the material [39], which will be related to the surface contact angle. The deposited alloying layers greatly increase the surface roughness and the exposed grain area and theoretically should promote cell adhesion, proliferation, and differentiation.…”

Section: Discussionmentioning

confidence: 99%

Study on Corrosion Resistance and Biological Properties of the Double Glow Plasma Nb-Zr Biological Implantation Alloying Layers

Zhao

Xiao

et al. 2022

Coatings

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In order to improve the corrosion resistance of implant materials and understand the corrosion mechanisms, we prepared a biomedical Nb-Zr alloying layer on 316L stainless steel using double-layer glow plasma surface-alloying technology and investigated the effects of gas pressures on its surface structure, mechanical properties, and corrosion behavior. In particular, the surface states of the substrate and alloying layers were investigated using 3D confocal micrographs, the water contact angle, and UV reflectance, which aims to study the effect of the surface quality on corrosion resistance and discuss the corrosion mechanisms. The results show that the working pressure has an effect on the current density, the sputtering amount of the alloying elements, and the diffusion process of the alloying elements during glow discharge. The Nb-Zr alloying layer prepared under a pressure of 40 Pa had a uniform and dense surface structure, and the distribution was island-like. A Nb-Zr alloying layer with a thickness of 15 μm was successfully obtained, including the diffusion layer and the deposition layer. Simultaneously, the elements Nb and Zr were gradually distributed along the depth, and a high Nb concentration formed in the Nb-Zr alloying layer. The solid solution formed by Zr in the Nb layer significantly improved the microhardness and corrosion resistance of the substrate. The Nb-Zr alloying layer prepared under a pressure of 40 Pa had the lowest corrosion current density and excellent corrosion resistance, which originated from the passive film formed by the Nb-Zr alloying layer that could inhibit the invasion of corrosive ions and improve the corrosion resistance. In addition, the Nb-Zr alloying layer could promote cell proliferation during long-term use and had good biocompatibility. Our study provides an efficient, high-quality processing method for the surface modification of biomedical metallic materials to form thicker Nb-Zr alloying layers as a cost-effective alternative to bulk Nb-based alloys.

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Investigation on the corrosion behavior and biocompatibility of Ti-6Al-4V implant coated with HA/TiN dual layer for medical applications

Cited by 65 publications

References 60 publications

Sol-Gel Derived Hydroxyapatite Coatings for Titanium Implants: A Review

Sol-Gel Derived Hydroxyapatite Coatings for Titanium Implants: A Review

Baicalein-modified hydroxyapatite nanoparticles and coatings with antibacterial and antioxidant properties

Study on Corrosion Resistance and Biological Properties of the Double Glow Plasma Nb-Zr Biological Implantation Alloying Layers

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