Particle breakage was reported to have great influence on the mechanical property of granular materials. However, limited studies were conducted to quantify the detailed effects of relative density and initial grading on the particle breakage behaviour of granular materials under different confining pressures. In this study, a series of monotonic drained triaxial tests were performed on isotropically consolidated granular materials with four different initial gradings and relative densities. It is observed that particle breakage increases as the confining pressure or relative density increases, whereas it decreases with the increasing coefficient of uniformity. Due to particle breakage, the grading curves of granular materials after triaxial tests can be simulated by a power-law function with fractal dimension. As the confining pressure increases, the fractal dimension approaches the limit of granular materials, i.e., 2.6. A unique normalized relation between the particle breakage extent and confining pressure by considering relative density and grading index was found.