Investigations and Outcomes for Olfactory Disorders

Luke, Louis; Lee, Liam; Jegatheeswaran, Lavandan; Philpott, Carl

doi:10.1007/s40136-022-00438-x

Cited by 4 publications

(8 citation statements)

References 78 publications

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“…The COS for olfactory disorders includes a mixture of qualitative and quantitative measures. For the objective measuring of smell and taste, the Sniffin Stick test or the University of Pennsylvania identification test (UPSIT) is recommended [69].…”

Section: Discussionmentioning

confidence: 99%

Delivery of Topical Drugs to the Olfactory Cleft

Espehana,

Lee,

Garden

et al. 2023

JCM

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Olfactory dysfunction affects approximately 20% of the population globally, with incidence increasing over the age of 60. The pathophysiology is complex, not yet fully understood, and depends on many factors, including the underlying cause. Despite this, the present literature on olfaction is limited due to significant heterogeneity in methodological approaches. This has resulted in limited effective treatments available for olfactory dysfunction. Medications for olfactory dysfunction can be administered locally (directly to the olfactory epithelium) or systemically (orally or intravenously). Currently, there are various methods for local drug delivery to the olfactory epithelium (nasal drops, nasal sprays, atomisers, pressured meter-dosed inhalers, rinses, and exhalation delivery systems). The aims of this review are to summarise the different methods of drug delivery to the olfactory cleft, evaluate the current literature to assess which method is the most effective in delivering drugs to the olfactory epithelium, and review the medications currently available to treat olfactory dysfunction topically. Going forward, further research is required to better establish effective methods of drug delivery to the olfactory epithelium to treat smell disorders.

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Section: Discussionmentioning

confidence: 99%

Delivery of Topical Drugs to the Olfactory Cleft

Espehana,

Lee,

Garden

et al. 2023

JCM

Self Cite

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“…Обоняние или нарушения вкуса могут быть количественными или качественными [24] и предположительно оказывают влияние на пищевое и социальное поведение, настроение, а также на качество жизни и работоспособность [25].…”

Section: влияние хемосенсорных систем на метаболические процессы в ор...unclassified

The impact of olfactory and gustatory perception on metabolic homeostasis in obese patients

Samoilova,

Podchinenova,

Matveeva

et al. 2023

Acta biomedica scientifica

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Obesity is currently a major global public health problem. As a result, in recent decades there has been a growing interest in studying the impact of this disease on the functioning of the central nervous system. One of the least understood aspects is the impact that obesity has on sensory systems.The olfactory and gustatory systems are closely related to various vital functions, such as the nocifensors activation, the stimulation of digestive reflexes. In addition, these sensory systems are known to play an important role in the mechanisms of food consumption through the regulation of appetite and satiety, influencing food choice and, therefore, they are involved in the development of obesity. A number of clinical studies have shown that obese patients are more likely to suffer from hyposmia compared to lean people of the same age.The reasons why this relationship exists remain largely unclear. The aim of this review is to assess the available data on this topic and to identify new promising areas for further research. The review was conducted in the PubMed databases for 2017–2023.

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“…Olfactory malingering has received less attention than visual or auditory malingering, even though it is relatively common. Although there are numerous causes of smell loss [17][18][19][20][21][22][23], most malingering occurs in cases where monetary incentives are involved. Smell loss in head trauma, for instance, (HT) is relatively common, with prevalence rates ranging from 20% to 61%, depending upon the severity of the trauma [24][25][26][27][28][29][30][31][32].…”

Section: Olfactory Malingeringmentioning

confidence: 99%

Sensory and Cognitive Malingering: Studies and Tests

Zucco

Sartori

2023

Sci

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Malingering relates to intentionally pretending or exaggerating physical or psychologic symptoms to gain an external incentive, such as avoiding work, law prosecution or military service, or seeking financial compensation from insurance companies. Accordingly, various techniques have been developed in recent years by the scientific community to address this challenge. In this review, we discuss malingering within visual, auditory and olfactory domains, as well as in cognitive disorders and psychopathology. We provide a general, critical, narrative overview on the intermodal criteria for differential diagnosis, and discuss validated psychophysical tools and electrophysiology-based tests for its detection, as well as insights for future directions.

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Investigations and Outcomes for Olfactory Disorders

Cited by 4 publications

References 78 publications

Delivery of Topical Drugs to the Olfactory Cleft

Delivery of Topical Drugs to the Olfactory Cleft

The impact of olfactory and gustatory perception on metabolic homeostasis in obese patients

Sensory and Cognitive Malingering: Studies and Tests

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