Investigations into Wave Propagation in Soft Tissue

Abstract

Abstract--In this article, the authors investigate wave propagation in soft-tissue matter with the aim of understanding the following: i) influence of nonlinear material properties of soft tissue on its mechanical response when subjected to transient loading and ii) mechanical response variation with respect to frequency and amplitude of the loading. To aid these investigations, reduced-order models are constructed taking into account available experimentally determined brain tissue properties and these models are used to study onedimensional wave propagation in brain tissue fiber bundles. These investigations could help in furthering the understanding of wave phenomena in a skull-brain system subjected to transient loadings.

Single-Molecule Conductance of Intramolecular Hydrogen Bonding in Histamine on Gold

“…We measured the conductance of hist at various pH conditions to probe the available conformations of the molecule on gold. hist has two p K a values of 6.04 and 9.75, corresponding to the protonation of N3/N1 of imidazole and the amino side group, respectively. We have previously shown that imidazole can bridge the junction electrodes through N3 and N1 sites when deposited out of solution with a pH above the N3/N1 p K a , typically around neutral pH .…”