For scramjet applications at low flight Mach numbers, decreased autoignition temperatures and shortened ignition delay times are essential. The possibility to influence these parameters with preseeded radicals is evaluated numerically using Cantera and a reduced GRI3.0 reaction scheme. It is found that single-digit ppm concentrations of OH-radicals can significantly reduce ignition delay. Combustion experiments are conducted to evaluate the possibility of producing radicals by catalytic fuel pre-treatment in hydrogen-air mixtures. While fuel equivalence ratios below Φ = 11 show an inhibiting effect due to increased water production, very high equivalence ratios show ignition promotion. Possibilities to further increase the ignition enhancement are discussed. Nomenclature Φ [-] equivalence ratio k r [mol, l, s] reaction rate constant A r [mol, l, s] pre-exponential factor T [K] temperature n r [-] factor for extended Arrhenius law E r [cal/mol] activation energy R m [J/(mol K)] ideal gas constant ∆t ign,X [ms] ignition delay time at temperature X p reactor [kPa]overall reactor pressure (absolute) T ignition [K] temperature measured at the reactor exit