Investigations on Parotid Gland Recovery after IMRT in Head and Neck Tumor Patients

Abstract

the mean dose, aV40 or aV26, revealed similar correlations with the excretion rate and with recovery. Hence, also absolute volumes can be used for treatment planning. Longer recovery times show higher ED50 values indicating partial regeneration of gland functions.

Critical discussion of evaluation parameters for inter-observer variability in target definition for radiation therapy

“…Advanced radiotherapy techniques like three-dimensional (3D) conformal or intensity-modulated radiotherapy aim to increase the dose in order to improve local control or reduce therapy-related side effects by conformal avoidance of organs at risk (OARs) [12,14,31,39]. Nevertheless, a safety margin has to be applied around the target volume, as uncertainties in treatment geometry can influence these aims [15].…”

Radio(chemo)therapy in the management of squamous cell carcinoma of cervical lymph nodes from an unknown primary site

“…Furthermore, the impairment of parotid gland function, resulting in xerostomia, is a frequent and dose-and volume-limiting side effect of RT in the head-and-neck region, which substantially impacts communication, quality of life, nutrition, and dentition [20,27].…”

Adaptive radiotherapy for soft tissue changes during helical tomotherapy for head and neck cancer

“…Soft tissue changes can also be assessed by daily computer tomographies (CT) performed for setup purposes during image-guided radiotherapy (IGRT) [3,4,18,19].…”