2024
DOI: 10.19163/2307-9266-2024-12-1-63-73
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Investigator’s influence on the muscle strength assessment in animals in experiment: Comparison of automated “inverted grid” test and its classical variant

P. R. Lebedev,
E. V. Kuzubova,
V. M. Pokrovsky
et al.

Abstract: The aim of the work was to study the influence of the researcher on the muscle strength assessment in animals in the experiment by comparing the results of the automated “inverted grid” test and its classical variant.Materials and methods. Male lines (Bla/J, n=20; FUS(1-359), n=20; Tau P301S+/+, n=20) and their background controls (C57BL/6J, n=20; CD1, n=20) were selected for the study. The dynamics of changes in the muscle deficit of the animals was evaluated in the automated and classical variant of the “inv… Show more

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