Knowledge processing has patterns which can be found in biological neuron activity and artificial neural networks. The work explores whether an underlying structure exists for knowledge which crosses domains. The results show common data processing patterns in biological systems and human-made knowledge-based systems, present examples of human-generated knowledge processing systems, such as artificial neural networks and research topic knowledge networks, and explore change of system patterns over time. The work analyzes nature-based systems, which are animal connectomes, and observes neuron circuitry of knowledge processing based on complexity of the knowledge processing system. The variety of domains and similarity in processing mechanisms raise the question: if it is common in natural and artificial systems to see this pattern-based knowledge processing, how unique is knowledge processing in humans.