Invited Perspective: Challenging the Dogma of Lead Neurotoxicity

Guilarte, Tomás R.

doi:10.1289/ehp13184

Environ Health Perspect

2023

DOI: 10.1289/ehp13184

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Invited Perspective: Challenging the Dogma of Lead Neurotoxicity

Tomás R. Guilarte

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2024

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Cited by 2 publications

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Impact of Cognitive Intervention on Neurocognitive Development of Schoolchildren Exposed to Lead in a Semi-Urban Community in Mexico

Cortez-Lugo,

Huanca-Laura,

Hernández-Bonilla

et al. 2024

Journal of Public Health Management &Amp; Practice

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Lead exposure is a severe public health issue that can adversely affect children’s neurocognitive development. A semi-urban community in Mexico has been exposed to lead from food cooked in glazed clay pots. A cognitive intervention was conducted from 2015 to 2016 to minimize this negative impact. This intervention aimed to improve the neurocognitive development of the affected children. Methods: A quasi-experimental study with a control group was conducted in children aged 7 to 12 years from 2 communities in Morelos, Mexico. Blood lead levels were determined, and the neurocognitive function was assessed pre- and postintervention with the Wechsler Intelligence Scale for Children and Children’s Auditory Verbal Learning Test-2. A cognitive intervention was conducted at the school. The difference-in-differences method adjusted for variables known as priori and evaluated the impact of cognitive intervention. Results: The differences-in-differences models indicated a significant average increase in scores on the Verbal Comprehension Index (9.58 points), Processing Speed Index (5.33 points), intelligence quotient (5.63 points) level of learning (7.66 points), interference trial (10.12 points), immediate memory span (7.98 points), and recognition accuracy (1.18 points) subtests after the cognitive intervention. Conclusion: The results suggest that cognitive intervention improves neurocognitive development in schoolchildren exposed to Pb.

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Impact of Cognitive Intervention on Neurocognitive Development of Schoolchildren Exposed to Lead in a Semi-Urban Community in Mexico

Cortez-Lugo,

Huanca-Laura,

Hernández-Bonilla

et al. 2024

Journal of Public Health Management &Amp; Practice

View full text Add to dashboard Cite

show abstract

Comment on “Neurotoxicity and Outcomes from Developmental Lead Exposure: Persistent or Permanent?”

Neuwirth,

Emenike

2024

Environ Health Perspect

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Invited Perspective: Challenging the Dogma of Lead Neurotoxicity

Cited by 2 publications

References 43 publications

Impact of Cognitive Intervention on Neurocognitive Development of Schoolchildren Exposed to Lead in a Semi-Urban Community in Mexico

Impact of Cognitive Intervention on Neurocognitive Development of Schoolchildren Exposed to Lead in a Semi-Urban Community in Mexico

Comment on “Neurotoxicity and Outcomes from Developmental Lead Exposure: Persistent or Permanent?”

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