Invitro Study of Thrombolytic Activity by Using Aqueous Preparation of Different Parts of Carica Papaya Plant Extract

Kalaiyarasi, L; sultana.D, Mubeen

doi:10.9790/3008-09323439

IOSRJPBS

2014

DOI: 10.9790/3008-09323439

|View full text |Cite

Invitro Study of Thrombolytic Activity by Using Aqueous Preparation of Different Parts of Carica Papaya Plant Extract

L Kalaiyarasi¹,

Mubeen sultana.D²

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

In Vitro study of Thrombolytic activity from the different parts of Carica papaya plant on COVID-19 patients.

Awais¹,

Afzal²,

Zahid³

et al. 2021

PBMJ

View full text Add to dashboard Cite

Background: Carica papaya plant has been used for medicinal purpose throughout the world because it have anti-inflammatory, anti-oxidant, antiviral, anti-cancer and wound healing like properties. Objective: The main object of this research was to evaluate the thrombolytic activity of Carica papaya plant in normal healthy individuals and COVID-19 patients to determine either parts of the plant (roots, seeds and leaves) exhibit more activity in normal persons or in COVID-19 patients. Material and method: For this study, total 20 blood samples were taken, 10 for normal individuals and 10 for positive COVID-19 patients. We used two different solvents i.e. autoclaved distilled water and concentrated methanol to prepare the 10% root, seed and leaf extracts of Carica papaya plant. For the thrombolytic activity of these plant extracts, samples were arranged as a triplicate for the accuracy of results percentage. Results: Our results evaluated that in normal individuals, distilled water root extract and methanolic seed extract exhibits maximum thrombolytic activity. The mean value with distilled water (root extract) and methanol (seed extract) is 36.9% and 32.9% respectively. While in covid-19 patients, distilled water leaf extract and methanolic leaf extract reveal maximum thrombolytic activity. In patients, the mean value with distilled water and methanol (leaf extract) is 21.8% and 23% respectively. Conclusion: In our study, we have observed that normal persons showed highly significant results as compared to COVID-19 patients. Because in COVID-19 disease, plasminogen activator inhibitor 1 (PAI-1), thrombin activatable fibrinolysis inhibitor and tissue plasminogen activator (tPA) factors elevate which results in hypo-fibrinolysis.

show abstract

In Vitro study of Thrombolytic activity from the different parts of Carica papaya plant on COVID-19 patients.

Awais¹,

Afzal²,

Zahid³

et al. 2021

PBMJ

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Invitro Study of Thrombolytic Activity by Using Aqueous Preparation of Different Parts of Carica Papaya Plant Extract

Cited by 1 publication

References 26 publications

In Vitro study of Thrombolytic activity from the different parts of Carica papaya plant on COVID-19 patients.

In Vitro study of Thrombolytic activity from the different parts of Carica papaya plant on COVID-19 patients.

Contact Info

Product

Resources

About