Involvement of basolateral amygdala‐rostral anterior cingulate cortex in mechanical allodynia and anxiety‐like behaviors and potential mechanisms of electroacupuncture
Yuerong Chen,
Siyuan Tong,
Yingling Xu
et al.
Abstract:AimsChronic pain is highly associated with anxiety. Electroacupuncture (EA) is effective in relieving pain and anxiety. Currently, little is known about the neural mechanisms underlying the comorbidity of chronic pain and anxiety and the EA mechanism. This study investigated a potential neural circuit underlying the comorbid and EA mechanisms.MethodsSpared nerve injury (SNI) surgery established the chronic neuropathic pain mouse model. The neural circuit was activated or inhibited using the chemogenetic method… Show more
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