Involvement of D1- and D2-like dopamine receptors in the dentate gyrus in the acquisition, expression, and extinction of the morphine-induced conditioned place preference in rats

Katebi, Najmeh; Farahimanesh, Sharareh; Fatahi, Zahra; Zarrabian, Shahram; Haghparast, Abbas

doi:10.1016/j.bbr.2018.07.018

Cited by 17 publications

(11 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The procedure on the second day was reversed and morphine was injected first followed by saline after 6 hr. The procedures on the last day of this phase were the same as the first day of the phase (Katebi, Farahimanesh, Fatahi, Zarrabian, & Haghparast, 2018).…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

D1- and D2-like receptors in the dentate gyrus region of the hippocampus are involved in the reinstatement induced by a subthreshold dose of morphine and forced swim stress in extinguished morphine-CPP in rats.

Norozpour

Zarrabian

Rezaee

et al. 2019

Behavioral Neuroscience

Self Cite

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

“…On the last day of the CPP phase (Day 5), the animal’s preference was measured by placing it in the neutral box with free access to all the compartments for 10 min. The conditioning score (the CPP score) was calculated as the difference of time spent in the morphine- and saline-paired compartments (Katebi et al, 2018).…”

Section: Methodsmentioning

confidence: 99%

D1- and D2-like receptors in the dentate gyrus region of the hippocampus are involved in the reinstatement induced by a subthreshold dose of morphine and forced swim stress in extinguished morphine-CPP in rats.

Norozpour

Zarrabian

Rezaee

et al. 2019

Behavioral Neuroscience

Self Cite

View full text Add to dashboard Cite

“…Notably, during CPP testing, entrance to the drug‐paired context is preceded by phase‐locked hippocampal theta rhythm (Takano, Tanaka, Takano, & Hironaka, ), suggesting the involvement of the hippocampus in reward memory retrieval of contextual cues. On a causative level, pharmacological disruptions or lesions of the hippocampus and dentate gyrus interfere with many stages of CPP, including the acquisition and retrieval of the drug/context association (Ebrahimian et al, ; Ferbinteanu & McDonald, ; Guo et al, ; Hernández‐Rabaza et al, ; Hitchcock & Lattal, ; Katebi, Farahimanesh, Fatahi, Zarrabian, & Haghparast, ; Meyers, Zavala, & Neisewander, ; Meyers, Zavala, Speer, & Neisewander, ; Milekic, Brown, Castellini, & Alberini, ; Rezayof, Zatali, Haeri‐Rohani, & Zarrindast, ; Sadeghi, Ezzatpanah, & Haghparast, ; Taubenfeld, Muravieva, Garcia‐Osta, & Alberini, ; Zarrindast, Nouri, & Ahmadi, ), and interfere with other animal models of addiction‐relevant behaviors (Fuchs et al, ; Ramirez et al, ; Paniccia et al, ). Such studies in laboratory animals support that the hippocampus and dentate gyrus play an important role in context‐dependent reward memory (Smith & Bulkin, ).…”

Section: Introductionmentioning

confidence: 99%

Image‐guided cranial irradiation‐induced ablation of dentate gyrus neurogenesis impairs extinction of recent morphine reward memories

et al. 2019

View full text Add to dashboard Cite

Dentate gyrus adult neurogenesis is implicated in the formation of hippocampal‐dependent contextual associations. However, the role of adult neurogenesis during reward‐based context‐dependent paradigms—such as conditioned place preference (CPP)—is understudied. Therefore, we used image‐guided, hippocampal‐targeted X‐ray irradiation (IG‐IR) and morphine CPP to explore whether dentate gyrus adult neurogenesis plays a role in reward memories created in adult C57BL/6J male mice. In addition, as adult neurogenesis appears to participate to a greater extent in retrieval and extinction of recent (<48 hr posttraining) versus remote (>1 week posttraining) memories, we specifically examined the role of adult neurogenesis in reward‐associated contextual memories probed at recent and remote timepoints. Six weeks post‐IG‐IR or Sham treatment, mice underwent morphine CPP. Using separate groups, retrieval of recent and remote reward memories was found to be similar between IG‐IR and Sham treatments. Interestingly, IG‐IR mice showed impaired extinction—or increased persistence—of the morphine‐associated reward memory when it was probed 24‐hr (recent) but not 3‐weeks (remote) postconditioning relative to Sham mice. Taken together, these data show that hippocampal‐directed irradiation and the associated decrease in dentate gyrus adult neurogenesis affect the persistence of recently—but not remotely—probed reward memory. These data indicate a novel role for adult neurogenesis in reward‐based memories and particularly the extinction rate of these memories. Consideration of this work may lead to better understanding of extinction‐based behavioral interventions for psychiatric conditions characterized by dysregulated reward processing.

show abstract

“…In this review, we only summarized the findings regarding the role of hippocampus in the retrieval of the memory, particularly in aversive memory and fear memory. This is a limitation that we did not cover other types or stages of memories, in which hippocampus has been demonstrated its involvements [156][157][158]. These need Withdrawal memory can be reactivated and become labile when the individual is exposed to the context which is associated with the withdrawal feelings.…”

Section: Discussionmentioning

confidence: 99%

The role of hippocampus in memory reactivation: an implication for a therapeutic target against opioid use disorder

Dai

Chen

et al. 2022

Curr Addict Rep

View full text Add to dashboard Cite

Purpose of the review The abuse of opioids induces many terrible problems in human health and social stability. For opioid-dependent individuals, withdrawal memory can be reactivated by context, which is then associated with extremely unpleasant physical and emotional feelings during opioid withdrawal. The reactivation of withdrawal memory is considered one of the most important reasons for opioid relapse, and it also allows for memory modulation based on the reconsolidation phenomenon. However, studies exploring withdrawal memory modulation during the reconsolidation window are lacking. By summarizing the previous findings about the reactivation of negative emotional memories, we are going to suggest potential neural regions and systems for modulating opioid withdrawal memory. Recent findings Here, we first present the role of memory reactivation in its modification, discuss how the hippocampus participates in memory reactivation, and discuss the importance of noradrenergic signaling in the hippocampus for memory reactivation. Then, we review the engagement of other limbic regions receiving noradrenergic signaling in memory reactivation. We suggest that noradrenergic signaling targeting hippocampus neurons might play a potential role in strengthening the disruptive effect of withdrawal memory extinction by facilitating the degree of memory reactivation. Summary This review will contribute to a better understanding of the mechanisms underlying reactivation-dependent memory malleability and will provide new therapeutic avenues for treating opioid use disorders.

show abstract

Involvement of D1- and D2-like dopamine receptors in the dentate gyrus in the acquisition, expression, and extinction of the morphine-induced conditioned place preference in rats

Cited by 17 publications

References 53 publications

D1- and D2-like receptors in the dentate gyrus region of the hippocampus are involved in the reinstatement induced by a subthreshold dose of morphine and forced swim stress in extinguished morphine-CPP in rats.

D1- and D2-like receptors in the dentate gyrus region of the hippocampus are involved in the reinstatement induced by a subthreshold dose of morphine and forced swim stress in extinguished morphine-CPP in rats.

Image‐guided cranial irradiation‐induced ablation of dentate gyrus neurogenesis impairs extinction of recent morphine reward memories

The role of hippocampus in memory reactivation: an implication for a therapeutic target against opioid use disorder

Contact Info

Product

Resources

About