Involvement of the penis by rectocolic adenocarcinoma

Abstract

A case report of a rectal carcinoma metastasizing to the penis is reviewed along with a total of 44 similar cases reported in the world literature. Pertinent arguments are presented in favor of yet another possible route of metastases, namely the perineural route, which has not been considered previously. Cavernosography provides valuable information about the extent of tumor spread; used more often, it would lead to recognition of the rare opportunity when an aggressive surgical approach might achieve prolonged survival.

Metachronous metastasis to the penis from carcinoma of the rectum

“…7 Penile metastases usually present on average 13 months after diagnosis of primary tumor and two-thirds have disseminated metastases at presentation. 1,2 The most common presenting symptoms in order are difficulty voiding, perineal pain, asymptomatic nodule and priapism. 1 The route of spread is contentious, but most authors favor retrograde venous spread from the pudendal venous system into the dorsal venous system of the penis.…”

“…1 The primary site of origin in order of frequency is bladder, prostate, rectum and recto sigmoid areas, and kidney. 1 Metastases to the penis from primary rectal tumors form an even smaller subgroup. A comprehensive literature review revealed only 35 cases occurring in the setting of a rectal primary carcinoma.…”

“…A comprehensive literature review revealed only 35 cases occurring in the setting of a rectal primary carcinoma. [1][2][3][4] We report a case of penile metastasis secondary to a primary rectal carcinoma and discuss the management of penile metastases.…”

Neįprastas tiesiosios žarnos vėžio metastazavimas: atvejo pristatymas

“…Nevertheless, by removing two cases where metastases appeared in the 9th and 26th year [2,3] after the primary treatment, the average onset of penile metastases was 25 months. Two-thirds of the patients had disse-minated metastases at presentation [4]. Occasionally, penile metastases can be a synchronous finding [5,6], or present as a leading symptom of the disease [6].…”

“…Total penectomy remains the only treatment to have shown a longer-term survival in patients with localized disease [7]. Surgery might also have a role in palliation where there is intractable penile pain [4].…”