Inzidentalome der Leber und der Gallenblase

Abstract

The expanding use of ultrasound in general practice is leading to an ever increasing rate of detection of true hepatic incidentaloma. The correct diagnosis of hepatic incidentaloma may be made in over 90% with non-invasive means. The questionable diagnosis of "symptomatic" incidentaloma should undergo close scrutiny prior to a decision in favour of surgery. With regard to more recent literature, the former "absolute" requirement for surgical resection in all cases of liver cell adenoma may have to be reappraised. Final inability to rule out malignancy represents an unquestionable indication for surgery in the light of low rates of morbidity and lack of mortality in this otherwise healthy patient group. Percutaneous biopsies should not be performed due to oncological hazards, indeterminate results and potential for acute complications.The stage-oriented radical re-resection following diagnosis of an incidentally detected gallbladder cancer may lead to significantly improved long-term survival, especially in the early tumour stages T1b and T2, which represents the most common stage of gallbladder cancer in incidentaloma. Patients at elevated risk for incidental gallbladder cancer should undergo thorough instruction with regard to the potential hazards of laparoscopic cholecystectomy. Multimodal therapeutic strategies directed at advanced stages of incidentally detected gallbladder cancer should be evaluated in prospective multicentre studies.

“Incidentaloma” of the Liver: Management of a Diagnostic and Therapeutic Dilemma

“…The continuous development of imaging techniques enables to diagnose asymptomatic liver lesions with an increasingly high sensitivity and specificity [11, 18, 32–36, 38]. Based on the morphological and functional behavior of the various imaging procedures, the dignity of these lesions may partly be determined unambiguously [1–4, 18, 32–36, 38].…”

“…Based on the morphological and functional behavior of the various imaging procedures, the dignity of these lesions may partly be determined unambiguously [1–4, 18, 32–36, 38]. This assignment and classification is more difficult for patients with a positive malignant, non-hepatogenous history of tumor (especially in case of a colorectal and breast carcinoma).…”

“…In the diagnosis of a hemangioma, the CM sonography, CT, or MRI is approximately equally effective [1, 3, 11, 18, 32–35]. With an MRI, a hemangioma can be diagnosed with a sensitivity of >95% and a specificity of 95% [1, 3, 11, 18, 32–35]. Method of choice in diagnosis of FNH is the MRI with liver-specific CM (e.g., gadoxetic acid; disodium salt (Primovist)).…”

“…Method of choice in diagnosis of FNH is the MRI with liver-specific CM (e.g., gadoxetic acid; disodium salt (Primovist)). The sensitivity is >95%; the specificity is >95% [3, 11, 18, 32–35]. The diagnosis of an adenoma is often difficult.…”

“…The diagnosis of an adenoma is often difficult. Method of choice is the MRI with liver-specific CM (e.g., gadoxetic acid; disodium salt (Primovist)) [1, 5, 11, 18, 32–35]. The diagnosis of a hepatocellular adenoma is only in premenopausal women with noncirrhotic liver, in case of the “classical” steroid-associated solitary adenoma, quite trivial to make [5].…”