Iodine-catalyzed amination of benzothiazoles with KSeCN in water to access primary 2-aminobenzothiazoles

Selective hydrogenation of phenols to cyclohexanols catalyzed by robust solid NHC–Rh coordination assemblies in water

“…To our delight, cyclohexanol 2 could be successfully obtained in H 2 O, a solvent widely acknowledged for its abundance, non-toxicity, and environmental compatibility. 59,60 This outcome confirmed our hypothesis that the NHC Rh complex exhibited hydrogenation activity in this vital transformation, even in water. When the reaction was carried out with 0.5 mol% bis-NHC-Rh complex 4, 1 mmol 1, and 5 mol% t-BuONa in H 2 O at 30 °C, 5 bar H 2 for 24 h yielded the highest output of 20%.…”

Fe(III)-Catalyzed N-Amidomethylation of Secondary and Primary Anilines with TosMIC

“…Base-metal catalysts have also emerged as potential alternatives to precious metal analogues . In regard to these principles, we have developed chalcogenation and chalcogenocyanation of imidazopyridines as well as amination of benzothiazoles in water . Cu-catalyzed C–H amination and alkylation of imidazopyridines have also been reported .…”