Iodine Intake, Excretion and Thyroidal Accumulation in Healthy Subjects<sup>1</sup>

Vought, R. L.; London, William T.

doi:10.1210/jcem-27-7-913

Cited by 57 publications

(46 citation statements)

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“…11 Median spot urinary iodine concentrations (as a biomarker for dietary iodine intake) 12 reflect iodine intake over the recent few days. Thresholds for median urinary iodine sufficiency have been identified for populations but not for individuals, given significant day-to-day variation of iodine intake.…”

Section: Methods To Assess Iodine Sufficiencymentioning

confidence: 99%

Iodine Nutrition in Pregnancy and Lactation

Leung

Pearce

Braverman

2011

Endocrinology and Metabolism Clinics of North America

110

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Section: Methods To Assess Iodine Sufficiencymentioning

confidence: 99%

Iodine Nutrition in Pregnancy and Lactation

Leung

Pearce

Braverman

2011

Endocrinology and Metabolism Clinics of North America

110

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“…A relatively large fraction of iodine excretion is via the urine (4-7). The minor portions are excreted in the feces, about 5-10%, and through perspiration (5,6,8). Iodine from ingested food initially circulates as iodide.…”

Section: Introductionmentioning

confidence: 99%

Estimation of Iodine Intake from Various Urinary Iodine Measurements in Population Studies

Vejbjerg

Knudsen

Perrild

et al. 2009

Thyroid

168

159

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“…This sug¬ gests that some subjects may have been losing approximately 10-20 % of their daily iodine intake in sweat. Another difficulty is the recent observation that many people over short periods are in negative iodine balance (Vought & London, 1967;Malvaux, Beckers & de Visscher, 1969). This means that urinary iodine excretion tends to overestimate daily intake.…”

Section: Resultsmentioning

confidence: 99%

Reduced Thyroid Activity in Jamaicans

Harland¹,

Richards²,

Goldberg³

1971

Journal of Endocrinology

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The results presented demonstrate reduced thyroid activity in euthyroid Jamaicans. In 15 subjects, thyroid clearance of 131I was 13\m=.\0\ m=+-\ 8\m=. \8(s.d.) ml/min, and renal clearance was 20\m=.\6\ m=+-\9\m=.\7 ml/min. In 205 healthy volunteers the 24 h 131I thyroid uptake averaged 13\m=.\8 % and in 60\m=.\9% the uptake was less than 10 % of the dose. Urinary excretion of 131I was correspondingly high. However, excretion of stable iodine in urine averaged only 62\ m=. \ 0\ g=m\ g/ day. Thyroid secretion rate (TSR) calculated in a group of subjects with complete collection of urine was 12\m=.\0\ g=m\gI/day in women and 11\m=.\4\g=m\gI/day in men. Protein-bound iodine (PBI) values in 50 subjects were 5\ m=. \ 9\ m=+-\ 1\ m=. \ 3\ g=m\ g/ 100 ml. Uptake of tri-iodothyronine by red blood cells also gave low values. The apparent discrepancy between low TSR and normal PBI is discussed. These findings, together with other reported values, indicate reduced thyroid activity in the tropics. It is argued that reduced metabolism is probably secondary to lower thyroid activity.

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Iodine Intake, Excretion and Thyroidal Accumulation in Healthy Subjects¹

Cited by 57 publications

References 0 publications

Iodine Nutrition in Pregnancy and Lactation

Iodine Nutrition in Pregnancy and Lactation

Estimation of Iodine Intake from Various Urinary Iodine Measurements in Population Studies

Reduced Thyroid Activity in Jamaicans

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Iodine Intake, Excretion and Thyroidal Accumulation in Healthy Subjects1

Cited by 57 publications

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Iodine Nutrition in Pregnancy and Lactation

Iodine Nutrition in Pregnancy and Lactation

Estimation of Iodine Intake from Various Urinary Iodine Measurements in Population Studies

Reduced Thyroid Activity in Jamaicans

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Resources

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Iodine Intake, Excretion and Thyroidal Accumulation in Healthy Subjects¹