Iodine/Oxone® oxidative system for the synthesis of selenylindoles bearing a benzenesulfonamide moiety as carbonic anhydrase I, II, IX, and XII inhibitors

Palomba, Martina; Angeli, Andrea; Galdini, Riccardo; Hughineata, Alexandra Joana; Perin, Gelson; Lenardão, Eder João; Marini, Francesca; Santi, Claudio; Supuran, Claudiu T.; Bagnoli, Luana

doi:10.1039/d4ob00826j

Org. Biomol. Chem.

2024

DOI: 10.1039/d4ob00826j

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Iodine/Oxone® oxidative system for the synthesis of selenylindoles bearing a benzenesulfonamide moiety as carbonic anhydrase I, II, IX, and XII inhibitors

Martina Palomba,

Andrea Angeli,

Riccardo Galdini

et al.

Abstract: A wide range of 3-selenylindoles were synthesized via an eco-friendly approach that uses Oxone® as oxidant in the presence of catalytic amount of iodine. This mild and economic protocol showed...

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Iodine/Oxone® oxidative system for the synthesis of selenylindoles bearing a benzenesulfonamide moiety as carbonic anhydrase I, II, IX, and XII inhibitors

Abstract: A wide range of 3-selenylindoles were synthesized via an eco-friendly approach that uses Oxone® as oxidant in the presence of catalytic amount of iodine. This mild and economic protocol showed...

Cited by 2 publications

References 66 publications

Synthesis of 1,4-benzodioxepines via electrochemical oxyselenenylation of 2-O-tethered alkenyl phenylmethanol and diselenides

Synthesis of 1,4-benzodioxepines via electrochemical oxyselenenylation of 2-O-tethered alkenyl phenylmethanol and diselenides

Exploring heterocyclic scaffolds in carbonic anhydrase inhibition: a decade of structural and therapeutic insights

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