Iodoxybenzoic Acid (IBX) in Organic Synthesis: A Septennial Review

Abstract

Visible light-induced reactions are a rapidly developing and powerful technique to promote organic transformations. They provide green and sustainable chemistry and have recently received increasing attention from chemists due to their wide application in organic synthesis. Light energy is eco-friendly, cheap, green, and inexhaustible with potential industrial and pharmaceutical applications. In this review, the most recent advances in visible light-induced reactions (2021-till date) have been highlighted.

Recent advances in TBHP‐promoted heterocyclic ring construction via annulation/cyclization

“…A thorough analysis of several synthetic methodologies that produced (CC), (CN), and (CS) bonds utilizing the I 2 /TBHP reagent system was compiled by Kapoor et al between 2010 and 2021 [14]. In keeping with our interest in investigating the uses of redox reagents [15–24], as of right now, there is not a thorough and critical evaluation of the literature on the applications of TBHP in heterocyclic ring formations. In this update, we discuss the most notable contributions of TBHP that have documented the scope of the reaction and provided mechanistic insights in heterocyclic ring formations from 2018 to date.…”