A conducting polymer was electrochemically prepared on a Pt electrode with newly synthesized 3'-(4-formyl-3-hydroxy-1-phenyl)-5,2' : 5',2''-terthiophene (FHPT) in a 0.1 M TBAP/CH 2 Cl 2 solution. The polymer-modified electrode exhibited a response to proton and metal ions, especially Al(III) ions. The poly [FHPT] was characterized with cyclic voltammetry, EQCM, and applied to the analysis of trace levels of Al(III) ions. Experimental parameters affecting the response of the poly [FHPT] were investigated and optimized. Other metal ions in low concentration did not interfere with the analysis of Al(III) ions in a buffer solution at pH 7.4. The response was linear over the concentration range of 5.0 Â 10 À8 -7.0 Â 10 À10 M, and the detection limit was 5.0 Â 10 À10 M using the linear sweep voltammetry (LSV). Employing the differential pulse voltammetry (DPV), the response was linear over the 1.0 Â 10 À9 -5.0 Â 10 À11 M range and the detection limit was 3.0 Â 10 À11 M. The relative standard deviation at 5.0 Â 10 À11 M was 7.2% (n ¼ 5) in DPV. This analytical method was successfully verified for the analysis of trace amounts of Al(III) ions in a human urine sample.