Ion Manipulation in Open Air Using 3D-Printed Electrodes

Build, Share and Remix: 3D Printing for Speeding Up the Innovation Cycles in Ambient Ionisation Mass Spectrometry (AIMS)

“…SIMION (https://simion.com, accessed on 27 October 2021) simulations indicated that higher pressures might be even advantageous for efficient ion transfer (see Figure 2E,F). Although the experimental performance for focusing nanoESI ions, monitored with an ion detection charge couple device (IonCCD) camera, is lower than expected, a high potential of optimising ion transfer tubes with 3D printing is evident [47].…”

“…Iyer et al [47] studied the impact of the geometry on ion transfer, using 3D printed electrodes made from conductive polymers. SIMION (https://simion.com, accessed on 27 October 2021) simulations indicated that higher pressures might be even advantageous for efficient ion transfer (see Figure 2E,F).…”

“…Without collision, ion transmission is prevented. Reprinted from [47] , with permission from the American Chemical Society, copyright 2019.…”

Leveraging 3D printing to enhance mass spectrometry: A review

“…One of the most attractive features of using 3D printing for the development of ion guiding structures is the very short time between running simulations to estimate ion trajectories, and the experimental verification of those simulations. Due to its low cost, ease of fabrication, and short production time, many different designs can be rapidly tested, as was done for 3D-printed focusing electrodes [54], and for 3D-printed drift tubes with one or multiple turns [55]. Importantly, the use of CAD software allows the precise definition of dimensions of a device e and these are then simply passed on to the printer for production, resulting in appropriate alignment between, in this case, conducting and insulating ring elements in a drift tube or ion funnel.…”

Multiplexing of Electrospray Ionization Sources Using Orthogonal Injection into an Electrodynamic Ion Funnel

“…50 Ambient ion beam merging and focusing using specially shaped 3D-printed devices and counter-propagating beams provides an opportunity to manipulate and combine multiple ion beams before they enter the vacuum system. 51,52 Despite the significant progress in this field, multiplexing of ion beams still results in a substantial ion loss, which motivates the development of new multiplexing strategies. An electrodynamic ion funnel is commonly used in both commercial and custom-designed mass spectrometers to facilitate ion transmission in the ESI interface.…”