Ion transfer stripping voltammetry for the detection of nanomolar levels of fluoxetine, citalopram, and sertraline in tap and river water samples

Izadyar, Anahita; Arachchige, Dinusha Ranawaka; Cornwell, Hayden; Hershberger, John C.

doi:10.1016/j.snb.2015.09.048

Cited by 49 publications

(39 citation statements)

References 39 publications

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“…Fluoxetine concentrations up to 0.01 g L -1 have been determined in WWTP effluents and up to 4.7 mg (kg of organic carbon) -1 has been found in sludges [1]. Furthermore, it has also been detected in drinking water at very low concentrations [1,5], which verifies the inefficiency of conventional treatments. Despite the low concentration of fluoxetine in the aquatic environment, several studies have revealed its bioaccumulation in fish tissues (from 0.14 to 1.02 g kg -1 ) [6,7] and its toxicity over algae and small invertebrates [8][9][10][11].…”

Section: Introductionmentioning

confidence: 96%

Abatement of the fluorinated antidepressant fluoxetine (Prozac) and its reaction by-products by electrochemical advanced methods

Salazar

Ridruejo

Brillas

et al. 2017

Applied Catalysis B: Environmental

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Abatement of the fluorinated antidepressant fluoxetine (Prozac) and its reaction by-products by electrochemical advanced methods, Applied Catalysis B, Environmental http://dx.GRAPHICAL ABSTRACT Fluoxetine hydrochloride (fluorinated antidepressant) 4 primary aromatics 1 chloroaromatic 4 carboxylic acids CO 2 F  NO 3  UVA light BDD(  OH)  OH Research Highlights Fluoxetine hydrochloride treated with Pt, RuO 2 -based or BDD anode and H 2 O 2 generation  Faster mineralization by PEF with a BDD anode due to BDD(  OH),  OH and UVA light  Pseudo-first-order decay by AO-H 2 O 2 , EF and, more rapidly, by PEF using a BDD anode  Degradation of fluoxetine with F  and NO 3  formation and partial Cl  oxidation to HClO  Detection of 4 primary aromatics, 1 chloroaromatic derivative and 4 carboxylic acids AbstractThe degradation of the fluorinated antidepressant fluoxetine, as hydrochloride, was comparatively studied in sulfate medium at pH 3.0 by anodic oxidation with electrogenerated H 2 O 2 (AO-H 2 O 2 ), electro-Fenton (EF) and photoelectro-Fenton (PEF). Experiments were performed with 100 mL solutions in an undivided tank reactor equipped with a Pt, RuO 2 -based or boron-doped diamond (BDD) anode and an air-diffusion cathode for continuous H 2 O 2 production. The BDD anode showed higher mineralization rate due to the great production of physisorbed BDD(  OH), which has larger reactivity to oxidize the drug and intermediates. The degradation rate was enhanced by EF with 0.50 mM Fe 2+ due to the additional production of  OH in the bulk from Fenton's reaction. The degradation was even faster using PEF owing to the additional photolytic action of UVA radiation.The most effective process was PEF with a BDD anode achieving 94% mineralization at 300 min.The fluoxetine decay followed a pseudo-first-order kinetics, being quicker in the order: AO-H 2 O 2 < EF < PEF. The effect of the current density and drug concentration on the mineralization rate and fluoxetine decay was clarified. Oxidation of fluoxetine by hydroxyl radicals yielded four aromatic by-products, as found by GC-MS. Additionally, a chloroaromatic compound was identified as a result of the reaction of active chlorine, which was formed in situ from the oxidation of chloride ion at the BDD anode. Four short-chain linear carboxylic acids, being oxalic and formic acid more abundant, were identified. In PEF, fluorine atoms of fluoxetine were completely released as fluoride ion, whereas the initial nitrogen was converted to nitrate ion in all cases. A reaction pathway for fluoxetine mineralization by the electrochemical advanced methods is finally proposed.

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Section: Introductionmentioning

confidence: 96%

Abatement of the fluorinated antidepressant fluoxetine (Prozac) and its reaction by-products by electrochemical advanced methods

Salazar

Ridruejo

Brillas

et al. 2017

Applied Catalysis B: Environmental

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“…Regarding the determination of dopamine and noradrenaline, the detection limits of 0.35 and 1.7 μM were achieved, respectively, and the selectivity coefficient obtained in the presence of ascorbic acid were 3.5 × 10 -4 for dopamine and 2.5 × 10 -3 for noradrenaline. Dopamine and daunomycin interaction at the ITIES with DNA was also reported by Ribeiro et al [93b] The detection at nanomolar levels of the drugs fluoxetine, citalopram and sertraline in drinking and river water was reported by Izadyar et al, [97] who employed a thin-film approach on a pencil lead electrodes for detection purposes. Tatsumi et al [20] investigated the transfer of cationic forms of tryptamine and serotonin across the water-NB interface by CV, and welldefined voltammetric waves were observed within the available potential window.…”

Section: Facilitated Ion-transfer (Fit) Reactionsmentioning

confidence: 59%

Electroanalytical Opportunities Derived from Ion Transfer at Interfaces between Immiscible Electrolyte Solutions

Arrigan¹,

Eulate²,

Liu³

2016

Aust. J. Chem.

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SummaryThis review presents an introduction to electrochemistry at interfaces between immiscible electrolyte solutions and surveys recent studies of this form of electrochemistry in electroanalytical strategies. Simple ion and facilitated ion transfers across interfaces varying from millimetre scale to nanometre scales are considered. Target detection strategies for a range of ions, inorganic, organic and biological, including macromolecules, are discussed.

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“…ITSV at the ITIES is known as a powerful electroanalytical method that not only enables the trace analysis of various ions but also, in comparison to traditional redox-based stripping voltammetry [10], the ions do not need to be reduced or oxidized. Stripping voltammetry at the ITIES has been used since the early 1990s [133], when it was demonstrated as a powerful platform for electroanalysis due to its high sensitivity, selectivity for a wide range of organic and inorganic analytes, requirement for low-cost equipment, versatility, and portability [3,9,67,125,[132][133][134][135][136]. Moreover, stripping voltammetry is attractive for in-situ analysis of protons of various macromolecules such as proteins, which are important in biological, biochemical, environmental, pharmaceutical, and clinical materials 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 analysis.…”

Section: Ion-transfer Stripping Voltammetry At the Micro-liquid/liquimentioning

confidence: 99%

“…A CP film tightly adheres to the PVC membrane to hinder the formation of a water layer. Several studies have shown that a double-polymer membrane using the ITSV method is an excellent technology for developing ion-selective electrodes with low detection limits [134,135,37,157,158].…”

Section: Potentiometry and Ion-transfer Stripping Voltammetry At The mentioning

confidence: 99%

“…More preconcentrated ion in the thin-layer membrane gives a smaller flux of ion from the aqueous phase to the PVC membrane. In 2016, Izadyar et al successfully applied a thin-layer, double-polymer membrane using ITSV to study the lipophilicity and nanomolar concentration of serotonin reuptake inhibitors, such as fluoxetine (Prozac ), citalopram (Celexa ), and sertraline (Zoloft ) in drinking and river water [135] ( Figure 6B). Her group also used the ion-transfer stripping voltammetry of hydrogen chromate ions on a PVC/POT-modified glass-carbon electrode to achieve a lower LOD of 12 nM Cr(VI) in drinking water [134] ( Figure 6A).…”

Section: Ion-transfer Stripping Voltammetry At a Thin-layer Liquid Mementioning

confidence: 99%

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Stripping Voltammetry at the Interface between two Immiscible Electrolyte Solutions: A Review Paper

Izadyar

2018

Electroanalysis

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Applying stripping voltammetry at interface between two immiscible electrolyte solutions (ITIES) leads to an electrochemical phenomenon that enables a very sensitive technique for detection at subnanomolar limits, which is useful for environmental, industrial, food‐safety, and medical purposes, as well as biomedical diagnostics. Studies on the molecular dynamics of the water/organic interface have provided information about the structure of this interface and the effect of molecular polarizability on interfacial properties of ITIES. The ion‐transfer stripping voltammetry (ITSV) technique was demonstrated as a powerful method due to its high sensitivity and its selectivity for a wide range of organic and inorganic analytes. This technique will lead to the industrial and miniaturized development of sensor technology for trace analysis. The purpose of this paper is to briefly review the history and most recent studies on stripping voltammetry at ITIES.

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Ion transfer stripping voltammetry for the detection of nanomolar levels of fluoxetine, citalopram, and sertraline in tap and river water samples

Cited by 49 publications

References 39 publications

Abatement of the fluorinated antidepressant fluoxetine (Prozac) and its reaction by-products by electrochemical advanced methods

Abatement of the fluorinated antidepressant fluoxetine (Prozac) and its reaction by-products by electrochemical advanced methods

Electroanalytical Opportunities Derived from Ion Transfer at Interfaces between Immiscible Electrolyte Solutions

Stripping Voltammetry at the Interface between two Immiscible Electrolyte Solutions: A Review Paper

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