“…However, it was found that large quantities could be observed to be lost, in those cases in which previous uptake had taken place in the absence of calcium (compare OVER-STREET, JACOBSON and HANDLEY 1952). These results are reminiscent of the classical studies on the beneficial effects of balanced salt solutions in particular of calcium containing solutions, on the structural properties of the protoplasm (FISCHER 1956, HELDER 1956). Overstreet et al ascribed their results to a higher stability of the rubidium binding entities in the cytoplasm.…”