Ionic liquid-promoted one-pot oxidative Michael addition of TMSCN to Baylis–Hillman adducts

Novel room temperature ionic liquid for fluorescence enhancement of Eu3+ and Tb3+

“…The chemical shifts for the 1 H in the benzoate group are also clearly evident. 13 Table 2 also confirm the characterization of this ionic liquid.…”

“…The 1 H and 13 Tables 2 and 3, respectively, together with their assignments. The chemical shifts of the protons assigned to the [bmim] group agree well with that reported in the literature by Bonhote et al [28] (except that for C8) and clearly confirms the presence of this cation group.…”

“…Ionic liquids are generally composed of large asymmetric cations, such as 1,3-dialkylimidazolium, N-alkylpyridinium, tetraalkylammonium, and phosphonium core with different anions, such as BF 4 À , PF 6 À , CF 3 SO 3 À , (CF 3 SO 2 ) 2 N À , NO 3 À , ClO 4 À and alkyl sulfate. These ionic liquids serve as novel solvents in various applications, such as liquid-liquid biphasic extraction processes [10,11], organic synthesis [12,13], electrochemical studies [14] and catalysis [15]. The properties that make these liquids unique and versatile as solvents, are the wide temperature range over which they exist as liquids, negligible vapor pressure, thermal stability, high ionic conductivity and recyclable nature.…”

Highly Efficient Syntheses of β‐Cyanoketones via Conjugate Addition of Me3SiCN to Aromatic Enones

“…9 Ionic liquid and microwave have also been applied to this reaction in line of the concept of green chemistry. 10,11 Recently, Shibasaki and co-workers developed an entirely distinct Ni(0)-cyclooctdiene (COD) complex in the elegant synthesis of Tamiflu, 12 an anti-influenza drug, and subsequent Ni(0) and Gd(OTf) 3 as the cooperative catalyst in the 1,4-addition of Me 3 SiCN to aliphatic enones with good substrate generality. 13 The first catalytic enantioselective version of conjugate addition of cyanide to enones is also described by Shibasaki.…”

The Highly Efficient 1,4-Addition of TMSCN to Aromatic Enones Catalyzed by CsF with Water as the Additive

“…9 Ionic liquid and microwave have been utilized in this reaction in line of the concept of green chemistry. 10,11 Recently, Shibasaki and co-workers applied an entirely distinct Ni(0)-cyclooctadiene (COD) complex to the elegant synthesis of Tamiflu, 12 an important anti-influenza drug, and subsequent Ni(0) and Gd(OTf) 3 as the cooperative catalyst to the 1,4-addition of TMSCN to a wide variety of aliphatic enones. 13 The first synthetically useful catalytic enantioselective conjugate addition of cyanide to enones is also documented by Shibasaki.…”