In this study, a real-time power estimation of a 250Wp solar panel is performed by using a commercial product SIS01-TC-T PV reference module and STM development board. Power estimation was carried out with Adaptive Neuro-Fuzzy Inference System (ANFIS). During the training process, the actual values of the Photo Voltaic (PV) panel with a 250Wp power were used. ANFIS training was accomplished with the hybrid learning algorithm. The power estimation process can be used as a reference power for various applications. The estimated power value can be used in real-time power monitoring for remote monitoring systems or optimum angle control applications for solar tracking mechanisms. It can also be used as a reference value for hybrid Maximum Power Point Tracking (MPPT) control applications or Proportional, Integral, and Derivative (PID) control. In addition, with this reference power value, the Pulse Width Modulation (PWM) signal required by various power electronics stages can be generated.