The incorporation of internet of things (IoT) technologies in the healthcare sector has ushered in a transformative era of patient care and medical practices. This chapter aims to share a thorough overview of the applications, benefits, challenges, and future prospects of IoT in healthcare and telemedicine. The chapter will explore the ways in which IoT is enhancing patient monitoring, diagnosis, treatment, and overall healthcare delivery. Additionally, it will delve into the ethical and security considerations linked with IoT in healthcare. This chapter will serve as an essential resource for healthcare professionals, researchers, policymakers, and technology enthusiasts seeking to understand and harness the potential of IoT in revolutionizing the healthcare industry.