“…Meanwhile, there are real-life problems, in which massive parallelization of computations on Apache Hadoop or Spark, and the use of scalable environments, like the Cloud, brought significant improvements in performance of data processing and analysis. Big data challenge was observed and solved in various works devoted to intelligent transport and smart cities [11,19,42,43,74,75,84], water monitoring [12,22,90], social networks analysis [13,14,77], multimedia processing [72,82], internet of things (IoT) [9], social media monitoring [50], Life sciences [3,31,32,44,58,69] and disease data analysis [6,45,81], telecommunication [27], and finance [2], to mention just a few. Many hot issues in various sub-fields of bioinformatics were also solved with the use of Big Data ecosystems and Cloud computing, e.g., mapping nextgeneration sequence data to the human genome and other reference genomes, for use in a variety of biological analyzes including SNP discovery, genotyping and personal genomics [65], sequence analysis and assembly [17,30,34,35,47,62], multiple alignments of DNA and RNA sequences [86,91], codon analysis with local MapReduce aggregations [63], NGS data analysis [8], phylogeny …”