Ipomea batatas Leaf Powder from Cameroon: Antioxidant Activity and Antihyperlipidemic Effect in Rats Fed with a High-Fat Diet

Fanmoe, Marcéline Joëlle Mbouche; Ngoune, Léopold Tatsadjieu; Ndjouenkeu, Robert

doi:10.1155/2021/5539878

Cited by 3 publications

(4 citation statements)

References 48 publications

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“…In addition to this, they also investigated the anthocyanin content and found proanthocyanidins content in the range from 175.27 g GAE/100 gDW to 176.04 mgCE/100 gDW. 5 Flavonoids act as an antioxidant with radical scavenger activity. The mechanisms of antioxidant action of flavonoids include suppressing reactive oxygen © 2023 the authors.…”

Section: Resultsmentioning

confidence: 99%

“…The different parts of this plant have been studied since they are used in folk medicine for the treatment of several disorders including acne and anemia, due to its antiviral applications, and agency as a anthelminthic vermifuge or dewormer. 5 In addition to their antidiabetic and antiviral properties, I. batatas leaves have been used to treat infectious disorders in Brazil. 6 Several studies on the leaves of I. batatas collected from Malaysia and Brazil have found excellent antioxidant activity due to the presence of flavonoids, β-carotene, anthocyanins and phenols.…”

Section: Introductionmentioning

confidence: 99%

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Phytochemical, Antioxidant and Antibacterial Evaluations of Ipomoea batatas L. from Riau, Sumatera Island, Indonesia

2023

TJNPR

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Indonesia is rich in its biodiversity of medicinal plants used traditionally for healing several ailments. Ipomoea batatas L., one of the traditional herbs of Indonesia that is popularly known as sweet potato, has played a significant role as a source of energy and phytochemicals in human nutrition and animal feeding. In traditional use, Ipomoea batatas (I. batatas) is effectively utilized in herbal medicine as an anti-inflammatory agent for treatment of illnesses and infectious oral diseases. This study aimed to evaluate the phytochemical screening, with the antibacterial and antioxidant activity of extracts of I. batatas leaves. Antibacterial effect was tested against Grampositive bacteria, Gram-negative bacteria and resistant bacteria through the agar disc diffusion method while antioxidant activity was analyzed using the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging method. The phytochemical screening showed the ethanol extract contains alkaloids, triterpenoids, flavonoids, tannins and saponins. The IC50 value for antioxidant properties was 233.476±0.01 ppm. Antimicrobial activity showed that percentage of inhibition growth was 83.61%. Ethanol extract showed the moderate antibacterial activity against Gram-positive bacteria, Staphylococcus aureus and Streptococcus mutans with diameter inhibition zone 8.7±0.01 cm and 10.2±0.3 cm in concentration 40%, respectively. Owing to the presence of its rich variety of secondary metabolites, the leaves extract of Ipomoea batatas L. is expected to exhibit more medicinal properties and be useful to develop as therapeutic agents in the future.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Phytochemical, Antioxidant and Antibacterial Evaluations of Ipomoea batatas L. from Riau, Sumatera Island, Indonesia

2023

TJNPR

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“…evaluated the effects of rich polyphenols star anis tea in HFD-sugar induced obesity rats, and they observed that the cholesterol levels were lower in the treatment groups . Furthermore, Mbouche Fanmoe et al in 2021 observed that Ipomea batatas Leaf powder reduced serum total cholesterol, LDL-cholesterol, and triglycerides in rats fed a high-fat diet, and this effect was attributed to the high content of polyphenols in the powder …”

Section: Resultsmentioning

confidence: 99%

Upcycled Romaine Lettuce Powder as a Dietary Supplement for Control of Metabolic Syndrome

García-Rocha,

Capaceta-Osuna,

Ochoa-Acosta

et al. 2023

ACS Food Sci. Technol.

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Romaine lettuce outer leaves are discarded in the field during harvesting, presenting an opportunity for upcycling. We previously developed a romaine lettuce powder (RLP) from discarded outer leaves with high antioxidant capacity, high levels of fiber, and high concentration of total soluble phenolics. In this study, we evaluated the health benefits and preventive effects of RLP in metabolic syndrome (MS) induced by a high-fat diet fed to mice for 12 weeks. Supplementation with 10% RLP in a high-fat diet lowered glucose and insulin levels and prevented the development of insulin resistance in mice. Moreover, adipose tissue weight was lower in mice fed with a high-fat diet supplemented with 10% RLP compared to mice fed with a control high-fat diet. Liver weight was also lower in mice fed with a high-fat diet supplemented with 10% RLP compared to those fed with low-fat and high-fat diet groups, suggesting a positive effect of lettuce powder on liver health. Here, we show that RLP has a preventive effect on MS by regulating body weight, lowering lipid levels, and improving glucose metabolism. Our results indicate that incorporating RLP into mice’s diet has potential health benefits.

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“…18 Ipomoea batatas leaf powder showed good antiradical activity and effectively reduced total cholesterol, triglyceride, and LDL cholesterol levels. [19][20][21] Metformin is a glucose-lowering agent, and its primary mechanism is inhibition of hepatic gluconeogenesis through activation of adenosine monophosphate kinase (AMPK), which suppresses glucagon-stimulated glucose production and increases glucose uptake via glucose transporter type 4 (GLUT4) in muscle and liver cells. [22][23][24]…”

Section: Discussionmentioning

confidence: 99%

Combination of purple sweet potato (Ipomoea batatas L.) leaf extract with metformin on blood glucose and total cholesterol levels of albino rats induced by high-fat diet and streptozotocin

Saing,

Harahap,

Sitorus

2024

Int J Basic Clin Pharmacol

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Background: Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to impaired insulin secretion, often accompanied by hypercholesterolemia. Metformin is a first-line antihyperglycemic drug that is often combined with other antihyperglycemic drugs. Purple sweet potato leaves have been widely studied to reduce glucose and cholesterol levels. Methods: This study was an experimental study using rats induced with a high-fat diet and streptozotocin, which were divided into 8 treatment groups, namely groups given CMC Na 0.5%, Metformin 45 mg/kg BW, Purple Sweet Potato Leaf Extract (SPLE) 200 mg/kg BW, SPLE 400 mg/kg BW, SPLE 800 mg/kg BW, SPLE 200 mg/kg BW with metformin 45 mg/kg BW, SPLE 400 mg/kg BW with metformin 45 mg/kg BW, and SPLE 800 mg/kg BW with metformin 45 mg/kg BW. Results: After treatment for 28 days with SPLE doses of 200 mg, 400 mg, and 800 mg/kg BW, both single doses and combinations with metformin showed a decrease in fasting blood glucose levels and total cholesterol, which were statistically significantly different (p<0.05) between treatment groups using the one-way ANOVA. The combination of SPLE 800 mg/kg BW with metformin normalized blood glucose levels of 93.50±4.93 mg/dl.Conclusion: The combination of purple sweet potato leaf extract with metformin is more effective in reducing blood glucose and total cholesterol levels compared to the single administration of metformin and SPLE.

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Ipomea batatas Leaf Powder from Cameroon: Antioxidant Activity and Antihyperlipidemic Effect in Rats Fed with a High-Fat Diet

Cited by 3 publications

References 48 publications

Phytochemical, Antioxidant and Antibacterial Evaluations of Ipomoea batatas L. from Riau, Sumatera Island, Indonesia

Phytochemical, Antioxidant and Antibacterial Evaluations of Ipomoea batatas L. from Riau, Sumatera Island, Indonesia

Upcycled Romaine Lettuce Powder as a Dietary Supplement for Control of Metabolic Syndrome

Combination of purple sweet potato (Ipomoea batatas L.) leaf extract with metformin on blood glucose and total cholesterol levels of albino rats induced by high-fat diet and streptozotocin

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