Iranian traditional medicinal plants for management of chronic heart failure: A review

Keihanian, Faeze; Moohebati, Mohsen; Saeidinia, Amin; Mohajeri, Seyed Ahmad

doi:10.1097/md.0000000000033636

Cited by 4 publications

(1 citation statement)

References 168 publications

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“…There is practical importance of different medicinal herbs such as Petroselinum crispum [ 28 ], peppermint [ 29 ] and many other edible plants in the management of chronic diseases [ 30 ]. Persian medicine has long‐utilised natural remedies [ 31 ], such as P. atlantica , for various diseases. In this randomised clinical trial, the effects of P. atlantica oleoresin in improving BP, BS and serum lipid levels were assessed in patients with Type 2 DM.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Effect of Pistacia atlantica Oleoresin on Blood Sugar, Pressure and Lipids in Patients With Type 2 Diabetes: A Single‐Blind, Placebo‐Controlled Trial

Memariani,

Tatari,

Zahedi

et al. 2024

Endocrino Diabet & Metabol

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BackgroundDiabetes mellitus (DM) is a chronic metabolic disorder characterised by high blood sugar (BS) levels due to impaired insulin production or insulin resistance. It is a global health concern with significant implications for morbidity and mortality. Persian medicine has long utilised natural remedies, such as Pistacia atlantica Desf., for various diseases. In this randomised clinical trial, the effects of P. atlantica oleoresin in the improvement of lipid profiles, glucose indices and blood pressure (BP) were assessed in patients with Type 2 DM.Materials and MethodsIn this randomised, single‐blind, placebo‐controlled study, 42 patients with Type 2 DM were randomly allocated to receive either P. atlantica oleoresin or placebo capsule for 3 months. Patients were evaluated prior to and 12 weeks after the beginning of the intervention, in terms of changes in lipid profiles, glucose indices and BP.ResultsAfter 3 months, the mean BP in patients with DM receiving P. atlantica oleoresin was significantly reduced compared with the baseline (p = 0.001). Also, these changes were significantly higher than those of the control group. The mean of total cholesterol (p = 0.89), low‐density lipoprotein (LDL) (p = 0.43) and triglyceride (TG) (p = 0.98) in the intervention group after 3 months was lower than that in the control group, but this difference was not statistically significant.ConclusionAfter 3 months, there was no significant difference between the P. atlantica and control groups in terms of blood sugar and lipid profiles. The mean BP in patients with DM receiving P. atlantica oleoresin was significantly reduced compared with that in the beginning of the study. Also, these changes were significant compared with the control group.

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