Iron-catalyzed borylation reactions: An overview

A pyridine-boryl radical mediated cascade reaction towards the synthesis of indolizines: a computational mechanistic analysis

“…Organoboron chemistry has long been recognized as a powerful platform for enabling a myriad of organic transformations and constructing complex molecular architectures. [1][2][3][4][5][6] The versatility of boron-containing compounds has been leveraged to facilitate innovations in organic synthesis, drug discovery, materials science, and beyond. Among the latest advancements, a particularly intriguing organoboron species, the boryl radical, has garnered substantial attention, revolutionizing the preparation and application of organoboron compounds.…”

Progress in the Electrochemical Synthesis of Organoboron Compounds

“…[38] Over the last few years, there has been a growing interest in developing practical and convenient methods for the synthesis of organoboron compounds, either by traditional organic synthesis based on highly reactive organolithium or Grignard reagents with electrophilic boron species, followed by transesterification and hydrolysis [39][40][41][42][43] or photochemical catalysis. [44][45] Over time, electrochemical borylation has emerged as a promising strategy to synthesize organoboron compounds; nevertheless, the number of electrochemical reports is negligible compared to other techniques such as conventional organic synthesis [46][47][48][49][50][51][52][53][54] or photoinduced borylation. [55][56][57][58] Therefore, there are great opportunities for the electrochemist to develop efficient borylation, which would sustainably expand the scope of organic electrosynthesis.…”

Aluminum–Boron Bond Formation by Boron Ester Oxidative Addition at an Alumanyl Anion

“…The identification of viable new borylation protocols is an important undertaking with relevance to a wide variety of onward cross-coupling processes and materials science applications. − Although much organoborane synthesis remains dependent on the uncatalyzed or catalyzed hydroboration of C–E multiple bonds with electrophilic B–H-containing molecules, , the last quarter century has witnessed significant progress in the development of borylation methods effected through the delivery of a formal boron nucleophile. − While a historic majority of this chemistry has been achieved through the generation of an isolable or intermediate transition metal boryl, − Yamashita and Nozaki’s realization of the sterically encumbered lithium boryl ( 1 , Figure ) in 2006 stimulated significant efforts to identify further M–B bonded molecules, − where M represents one of the more electropositive elements of the periodic groups 1, 2, or 13.…”

“…6 -benzene before the addition of 2 equiv of N,N′diisopropylcarbodiimide (15.6 μL, 12.6 mg, 0.1 mmol) via a micropipette into the colorless solution. No reaction was observed by…”