Iron contamination of two local alcoholic drinks

Gazuwa, Samuel Y.; Dabak, Jonathan D.; Ubom, G A

doi:10.4314/jmt.v8i1.35191

Cited by 5 publications

(9 citation statements)

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“…These cooking vessels are constructed from unsuitable metal or metal alloys which easily get corroded by cooking water thus introducing trace elements such as Zn, Cu Fe into the beverage (Okoye, 1990;Gazuwa et al, 2006). Ubom and Okoye (1992) have reported a pH-dependent contamination of Burukutu by iron (Fe) and that the equilibrium favoured the leaching of iron into the beverage.…”

Section: Discussionmentioning

confidence: 99%

“…It is implicated in causing decreased absorption of Fe and thus may lead to anaemia, inhibition of the Cumetalloenzymes, also linked to hepatitis and post hepatic cirrhosis, irreversible nervous system breakdown and blocks calcium channels and depletes dopamine which leads to Parkinson's disease (Internet Health Report, 2007). Gazuwa et al (2006) have reported iron (Fe) as contaminant of Pito and Burukutu and their pH values were 3.3 and 3.2 respectively. At this acidic pH, the tendency is for these metals to undergo reduction to other salts or compounds or even the elemental form which could spark off lethal consequences.…”

Section: Discussionmentioning

confidence: 99%

“…Contaminants have been reported to be present in foods including local alcoholic drinks (Okoye and Ekpengyong, 1984;Obasi et al, 1987;Gazuwa et al, 2006). These contaminants could be organic or inorganic elements such as copper (Cu), iron (Fe), manganese (Mn) and zinc (Zn).…”

Section: Introductionmentioning

confidence: 99%

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Contaminants in local alcoholic beverages: zinc and manganese contamination

Gazuwa¹,

Daback²,

Ubom³

2009

International Journal of Biological and Chemical Sciences

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The extent of leaching of zinc (Zn) and manganese (Mn) from the vessels used during the preparation of two local alcoholic drinks, Pito and Burukutu has been assessed. Leaching of these metals during the four phases of fermentation was monitored by determining the levels of the metals in each phase using atomic absorption spectrophotometric technique; in each complete fermentation protocol, metallic or clay container was used. Contamination appeared to be due to the fermentation process, container used or a combination of the two. Comparatively, there was increase in the levels of these metals from the initial to the final phase of fermentation for both types of vessels; in each case, appropriate controls were used. Compared to control values, the average increase in the level of zinc in Burukutu and Pito for metallic and clay containers is 343%; 325% and 295%; 252% respectively; whereas for manganese the increases are 815%; 1438% and 1292%; 1150% in that order. The differences in the levels of these metals among the phases in each of the drinks were significant (p<0.05).

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Contaminants in local alcoholic beverages: zinc and manganese contamination

Gazuwa¹,

Daback²,

Ubom³

2009

International Journal of Biological and Chemical Sciences

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“…This occurs across a spectrum from fatty liver, to acute alcoholic hepatitis, to cirrhosis or liver cancer (Frank et al, 2004). Even though alcohol is toxic, its toxicity is increased in the presence of heavy metal salts (Gazuwa et al, 2006). Gazuwa et al (2014) reported that, in alcoholic environment, cadmium and lead salts elevated serum activities of AST, and ALP; also, the levels of UR and CR.…”

Section: Discussionmentioning

confidence: 99%

“…Ethyl alcohol and some metabolites such as ethanal in 'brew' are the main intoxicating substance in all alcoholic drinks. Gazuwa et al (2006) reported significant levels of iron in burukutu and pito brewed in both metallic and clay containers. These native beers were also reported to be contaminated with zinc and manganese (Gazuwa et al, 2008).…”

Section: Introductionmentioning

confidence: 97%

Effects of alcoholic solutions of three salts of metals on some hepatorenal biochemical parameters in albino Wistar rats

Gazuwa¹,

Pipkong²,

Pofi³

2018

Int. J. Bio. Chem. Sci

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Toxicants are present in alcoholic drinks both of which are toxic to the liver and kidney. But do combination of two heavy and one trace metal salts affect the toxicity of alcohol in vivo? This work sought to compare effects of alcohol alone (control), with alcoholic solutions of salts of Cd, Pb, Zn and Mn on liver and kidney parameters. Further, to compare toxic effects of Cd and Pb in presence of Zn and also in the presence of Mn. To unravel this, 20 male albino Wistar rats were divided into 5 groups of 4 rats each and orally administered appropriate doses of alcoholic solution containing Pb(CH 3 CH 2 OO-) 2 +CdCl 2 +ZnSO 4 (A), in one case and Pb(CH 3 CH 2 OO-) 2 + CdCl 2 +MnCl 2 (B) in the other based on 10 ml/kg volume selection calculations. Rats were fed once daily and spectrophotometry was applied for the analysis. The control contained 5% (v/v) alcohol concentration. Treatment with A, for 7 and 14 consecutive days significantly (p<0.05) elevated serum activities (IU) of aspartate oxaloacetate transaminase (AST), 241.51±0.47, alanine transaminase (ALT), 69.43±.35 compared to control group values except alkaline phosphatase (ALP), 154.86±0.55 (p>0.05). Mean serum levels of total proteins (TP), in gdm-3 , was 73.81±0.65 (p<0.05); levels of urea (UR) and creatinine (CR), mMoldm-3 , were 37.38±0.32 and 39.75±0.45 respectively (p<0.05) relative control group values. B administered for 7 and 14 days significantly increased (p<0.05) activities of AST, ALT, ALP as well as ALB, UR (251.25±2.11, 87.43±3.12, 245.19±2.31, 37.34±1.49, 7.47±0.64) respectively; levels of TP and CR were not significantly higher (P>0.05) relative control group values. Whereas treatment with A elevated the hepatic parameters, treatment with B raised the concentration of the nephrotic parameters. Since cadmium and lead salts were common to both A and B, ZnSO 4 appeared to mitigate the adverse effects of both salts on the liver better than MnCl 2 which, in turn, modulated effects on the kidney better. It would mean therefore that Cd and Pb aggravate the hepato-nephrotic toxicity of alcohol. Presence of Zn and Mn reduced the adverse effects of the salts on hepatic and nephrotic biochemical parameters in male Wistar rats respectively.

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Assessment of Metabolites Content of Native Alcoholic Beverages Obtained from Jos, Nigeria

Gazuwa¹,

Dabak²,

Jaryum³

et al. 2020

IJFSB

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Burukutu, (BKT) Pito (PT) and Goskolo (GSK) are drinks consumed routinely within the area of study. Although consumption of GSK is illegal owing to its life threatening toxicity, people still consume it secretly. Whereas BKT and PT are locally prepared using unscientific methods in preparing the drinks, GSK is a mixture containing different compounds and chemicals. BKT and PT are more commonly ingested than GSK. Because methods applied during 'brewing' BKT and PT are not scientific, toxic metabolites might be generated. So, the drinkers are prone to their toxic effects. This work ascertained the presence and levels of unwanted metabolites in these drinks using Gas chromatographic-Mass spectrometric (GC-MS) technique. Metabolites could aggravate the toxicity of alcohol and alcohol-related disease conditions. Results, (% relative abundance), showed the significant presence in BKTof6-Octadecanoic acid (38.51),

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Iron contamination of two local alcoholic drinks

Cited by 5 publications

References 0 publications

Contaminants in local alcoholic beverages: zinc and manganese contamination

Contaminants in local alcoholic beverages: zinc and manganese contamination

Effects of alcoholic solutions of three salts of metals on some hepatorenal biochemical parameters in albino Wistar rats

Assessment of Metabolites Content of Native Alcoholic Beverages Obtained from Jos, Nigeria

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