Iron Deficiency Anaemia:-Comparison of Efficacy and Tolerability of Iron Polymaltose Complex with Ferrous Sulfate

Chaudhari, Devendra R.; Bite, Bapurao M.; Chopade, Suyog S.

doi:10.5958/2321-5836.2015.00014.2

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It results from an inadequate dietary intake of iron, inadequate iron absorption or blood loss. 3 The requirement of iron increase during pregnancy, specially in the third trimester. A pregnant woman needs six times more iron than a nonpregnant woman.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Efficacy and Tolerability of Ferrous Sulfate and Carbonyl Iron in Iron Deficiency Anemia in Pregnant Woman

Ahmed¹,

Shahriar²,

Iqbal³

et al. 2022

Sir Salimullah Med. Coll. J.

View full text Add to dashboard Cite

Introduction: Iron deficiency anemia in pregnancy is common and causes a huge burden globally. Bangladesh is known to have a high prevalence of iron deficiency anemia in pregnant women. Hence, it is important to evaluate the efficacy and tolerability of drugs in treatment of iron deficiency anemia in pregnancy. Objective: The purpose of present study was to compare the efficacy and tolerability of Ferrous Sulfate and Carbonyl Iron in Iron Deficiency Anemia in pregnant women. Methodology: An observational prospective study was conducted in obstetric and gynae out – patient department of Sir Salimullah Medical College and Mitford Hospital. Woman between 16 – 28 weeks of pregnancy with haemoglobin level 7 – 10 g/dl with microcytic hypochromic blood film were included in this study. Pregnant women in 1st and 3rd trimester of pregnancy were excluded from the study. Among the study population one group was given Tablet Ferrous Sulfate and another group was given Capsule Carbonyl Iron. Results: There was significant and comparable rise in HB in 4th, 8th and 12th week in the two group. (p<0.001). Carbonyl iron showed significantly more rise in Hb as compared to Ferrous Sulfate. Adverse effects were seen more in number and intensity with Ferrous Sulfate. Individual efficacy of both compounds was good but Carbonyl Iron was better tolerated. Conclusion: Carbonyl Iron is more effective and tolerable than Ferrous Sulfate in treatment of iron deficiency anemia in pregnancy. Sir Salimullah Med Coll J 2022; 30: 83-88

show abstract

Section: Introductionmentioning

confidence: 99%

Comparison of Efficacy and Tolerability of Ferrous Sulfate and Carbonyl Iron in Iron Deficiency Anemia in Pregnant Woman

Ahmed¹,

Shahriar²,

Iqbal³

et al. 2022

Sir Salimullah Med. Coll. J.

View full text Add to dashboard Cite

show abstract

Utility of Automated Reticulocyte Research Parameters derived from Beckman Coulter DXH800 in Nutritional Deficiency Anaemias

Khanna,

Saeed,

Manohar

et al. 2023

RJPT

View full text Add to dashboard Cite

Introduction: Reticulocyte parameters obtained from the automated analyzers have gained importance not only in the classification of anemias but also in therapeutic monitoring. Their role in nutritional anemia is by far limited to monitoring the hematinic response. The present study aims to describe the distribution of various reticulocyte parameters obtained from Beckman Coulter DXH 800 in cases of nutritional deficiency anemias. Method: Reticulocyte parameters of iron deficiency anemia (IDA) (n=146), megaloblastic anemia (MA) (n=119), and mixed deficiency anemia (n=32) were compared with a non-anemic healthy control group (n=68). Independent sample T-test and one-way ANOVA were used for comparisons. Results: The RET%, MRV, IRF, MSCV, HLR%, RSF, RDWr, and RDWr-SD were significantly higher in MA than in other groups and a significant inverse correlation of Hb was seen with MRV, RDWr, and RDWr-SD. In IDA there was a significant increase in RET%, ARC, IRF, HLR%, HLR#, and RDWr, and a reduction in MRV, MSCV, and RSF. The strongest positive correlation of Hb was with RSF. In the mixed deficiency anemia group, there was an increase in RET%, ARC, IRF, HLR%, HLR#, and RDWr and a reduction in MRV, MSCV, and RSF. Cases on treatment had significantly higher RET%, ARC, and HLR# compared to those without irrespective of etiology. Conclusion: The study strengthens the utility of RSF as a marker of iron-restricted erythropoiesis, and a low RSF and higher MRV in differentiating IDA from mixed deficiency anemia. Irrespective of the etiology, RET%, ARC, HLR%, and HLR# can be utilized for monitoring therapy in nutritional anemias.

show abstract

Iron Deficiency Anaemia:-Comparison of Efficacy and Tolerability of Iron Polymaltose Complex with Ferrous Sulfate

Cited by 2 publications

References 0 publications

Comparison of Efficacy and Tolerability of Ferrous Sulfate and Carbonyl Iron in Iron Deficiency Anemia in Pregnant Woman

Comparison of Efficacy and Tolerability of Ferrous Sulfate and Carbonyl Iron in Iron Deficiency Anemia in Pregnant Woman

Utility of Automated Reticulocyte Research Parameters derived from Beckman Coulter DXH800 in Nutritional Deficiency Anaemias

Contact Info

Product

Resources

About