Iron-deficiency anemia in children: from diagnosis to treatment

Lee, Jae Hee

doi:10.5124/jkma.2016.59.9.678

Cited by 4 publications

(3 citation statements)

References 10 publications

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“…In infant and preschool children (＜5 years of age), rapid growth consumes the iron stores that were absorbed from the mother during gestation, leading to ID. Indeed, low birth weight, prematurity, consumption of cow's milk before 12 months, and breastfeeding alone without additional iron supply after 6months of age are high risk factors for IDA in children ＜5 years of age [2,23]. Adolescents, especially girls, are also at a particularly high risk of ID due to rapid growth and menstrual iron losses.…”

Section: ) Physiologic Individuals Risk Factorsmentioning

confidence: 99%

“…More effective iron absorption and the rapid recovery of hemoglobin levels in IDA patients with low hepcidin levels [3]. The total iron consumption period is about 3 to 6 months, since after the hemoglobin is normalized, it is necessary to take iron supplement for 8 weeks for repletion of iron stores in the body [2]. However, side effects are reported up to 30-70% of patients, which limits long term use of oral iron [42,43].…”

Section: Therapymentioning

confidence: 99%

“…It is estimated that 30-50% of the global population has IDA and the prevalence of ID worldwide is twice as high as that of IDA [2,3]. The prevalence is now highest in Central and West Africa and South Asia, particularly 58% and 71% in children younger than 5 years, respectively [1,4].…”

Section: Introductionmentioning

confidence: 99%

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Iron Deficiency Anemia

Lee

2020

Clin Pediatr Hematol Oncol

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Iron deficiency anemia (IDA) is a common medical problem that affects an estimated 30-50% of the world's population. The causes of IDA are malnutrition, rapid growth with improper dietary iron, blood loss through gastrointestinal tract or menstruation. The genetic factors of iron-refractory iron deficiency anemia have also been identified. Previous studies on the theory of hepcidin-based homeostatic regulation have helped increase our understanding of iron metabolism. Symptoms of anemia may include non-specific symptoms, such as pale appearance, fatigue, weakness, and decreased appetite, as well as impaired neurocognitive functions, including delay mental development and restless leg syndrome. IDA can be diagnosed by laboratory findings. The conventional tests that are typically performed to diagnose IDA include hemoglobin level, serum iron, transferrin saturation, and ferritin level, as well as soluble transferrin receptor, hepcidin level, zinc protoporphyrin, reticulocyte hemoglobin content. Treatment begins with an accurate diagnosis, and both oral and parenteral iron can be used. Symptoms improve quickly after treatment; however, the diagnosis and treatment of IDA is rather overlooked. Therefore, it is necessary to better understand the disease process of IDA, make an accurate diagnosis, and prescribe essential iron supplements to patients with symptoms.

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Section: ) Physiologic Individuals Risk Factorsmentioning

confidence: 99%

Section: Therapymentioning

confidence: 99%

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Iron Deficiency Anemia

Lee

2020

Clin Pediatr Hematol Oncol

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Simultaneous Determination of Chromium and Iron in Powdered Milk Using High-Resolution Continuum Source Graphite Furnace Atomic Absorption Spectrometry

et al. 2019

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Assessment of micronutrients in pediatric vertigo

Aydın,

Bucak,

Geyik

2024

ADYÜ Sağlık Bilimleri Derg

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Aim: This study aimed to evaluate the clinical characteristics of patients admitted to the pediatric neurology outpatient clinic with the complaint of vertigo and to investigate the role of micronutrients in the etiology of vertigo Materials and Methods: This study retrospectively evaluated the patients aged four to 18 years who were admitted to the pediatric neurology outpatient clinic with the complaint of vertigo to evaluate the clinical characteristics and the role of micronutrients in the etiology of vertigo. Patients, for whom the Z00.1 code, the routine child health examination code, was entered in the pediatric outpatient clinic in the same period when the patients presented with the complaint of vertigo were included as the healthy control group. Hemogram and hormone profiles [25(OH)D, FT4, TSH, vitamin B12, folic acid and ferritin] of the groups were compared. Results: There was no statistically significant difference between the study group and healthy controls in terms of age and gender. Hematocrit (p<0.001), platelet (p<0.001), vitamin B12 (p=0.015), vitamin D (p=0.043) and TSH (p=0.013) levels were found to be significantly lower in the vertigo group compared to the control group. Conclusion: The importance of micronutritional deficiencies cannot be denied in patients presenting with vertigo symptoms. Main point that makes our study valuable is that there are limited number of studies in the literature comparing laboratory parameters of pediatric patients with vertigo symptoms and healthy controls. There is a need for prospective studies, involving more cases and awareness on this issue.

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Iron-deficiency anemia in children: from diagnosis to treatment

Cited by 4 publications

References 10 publications

Iron Deficiency Anemia

Iron Deficiency Anemia

Simultaneous Determination of Chromium and Iron in Powdered Milk Using High-Resolution Continuum Source Graphite Furnace Atomic Absorption Spectrometry

Assessment of micronutrients in pediatric vertigo

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