2000
DOI: 10.1079/095442200108729070
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Iron fortification of infant formula

Abstract: The purpose of this review is to examine the need for and appropriate level of Fe forti®cation of infant formula, and to assess any adverse effects of Fe forti®cation. The appropriate level of Fe forti®cation of infant formula has been established through studies of Fe absorption or erythrocyte incorporation of Fe, and through clinical trials of formulas with varying levels of Fe that were aimed at preventing the development of Fe de®ciency in participating infants. In addition, the effects of varying levels o… Show more

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Cited by 11 publications
(7 citation statements)
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“…1,2 For instance, infant formula in Europe typically contains lower amounts of iron than in the United States (approximately 4-7 mg/L compared with 12-13 mg/L). 1,3 Concerns have been raised about providing iron to iron-sufficient infants, including poorer growth and increased morbidity. 4 We have not ob-served such effects, 5 but it is reasonable to wonder whether there might be risks to the developing brain.…”
mentioning
confidence: 99%
“…1,2 For instance, infant formula in Europe typically contains lower amounts of iron than in the United States (approximately 4-7 mg/L compared with 12-13 mg/L). 1,3 Concerns have been raised about providing iron to iron-sufficient infants, including poorer growth and increased morbidity. 4 We have not ob-served such effects, 5 but it is reasonable to wonder whether there might be risks to the developing brain.…”
mentioning
confidence: 99%
“…Furthermore, there are significant worldwide differences in average formula iron content: the average iron content in iron-fortified infant formulas in Europe and other countries tends to be less than in the United States (4–7 mg/L vs. 12–13 mg/L). [4,15,16] Patients with a negative response to the iron-containing foods question or an affirmative response to the low iron formula question were coded as true for a low-iron diet before 12 months of age.…”
Section: Methodsmentioning
confidence: 99%
“…Fortification of food vehicles with absorbable iron is probably the most cost‐effective primary prevention strategy to prevent ID but does depend upon there being within a community a suitable milk or staple food that is consumed in adequate quantities. Fortification of formula feeds (Moy, 2000), commercially prepared weaning foods, bread flour, breakfast cereals and condiments, such as salt, sugar and curry powder have all been tried (Hurrell, 1997). However, the effectiveness of food fortification is limited by bioavailability of iron in cereal‐based foods, the ability of the gut to absorb increasing concentrations of iron, and by the adverse effects of iron on the food vehicle that limit shelf life, cause discolouration and metallic taste.…”
Section: Iron Fortification Of Foodmentioning
confidence: 99%