Iron(III)-induced activation of hydrogen peroxide for oxidation of 2-methylnaphthalene in glacial acetic acid

Synthesis of Fe 3 O 4 @SiO 2 @OSi(CH 2 ) 3 NHRN(CH 2 PPh 2 ) 2 PdCl 2 type nanocomposite complexes: Highly efficient and magnetically-recoverable catalysts in vitamin K 3 synthesis

“…Acetic acid joins into the oxidation mechanism together with catalysts by transporting oxygen to aromatic ring (Kowalski et al;Narayanan et al, 2002;Shimanskaya et al, 2014;Zalomaeva et al 2007;Florea et al, 2014 Phosphines-metal complexes (especially Pd(II) and Pt(II)) are known as efficient catalysts in oxidation reactions using peroxides Florea et al, 2014). Even though all the complexes show good activity, Fe 3 O 4 @L1-Pd(II) complex showed the best catalytic activity and the best selectivities compared with the literature Florea et al, 2014;Kowalski et al, 2003;Anunziata et al, 2004Shimanskaya et al, 2014Yube;& Mae, 2005;Narayanan et al, 2002). Selectivites reached to 60-65 % with 95-99 % conversions ( Figure 5, Table 1).…”

“…Vitamin K 3 (2-methyl-1,4-naphthoquinone or menadione) is a synthetic chemical compound of vitamin K group and used as a nutritional supplement especially in feed of chickens and fishes as in vitamin premixes and also used for new-borns. It is related to blood coagulation and the body needs for controlling binding of calcium in bones and other tissues (Florea et al, 2014, Kowalski et al, 2003, Narayanan et al, 2002, Shimanskaya et al, 2014, Zalomaeva et al 2007). The lack of vitamin K causes bones weaken and promote calcification of arteries and other soft tissues.…”

“…In order to synthesis of 1 kg vitamin K 3 , 18 kg. chromium containing waste is obtained and the treatment of chromium containing waste is quite difficult (Kowalski et al, 2003;Narayanan et al, 2002;Shimanskaya et al, 2014;Zalomaeva et al 2007). Classical oxidation process having Cr(VI) in sulfuric acid has also low selectivity and efficiency (Kowalski et al, 2003;Narayanan et al, 2002;Shimanskaya et al, 2014;Zalomaeva et al 2007;.…”

“…Menadione can be produced with the catalytic oxidation oxidation of 2-methylnaphthalene or 2-methyl-1-naphthol in different solvents by hydrogen peroxide, oxygen or other chemical oxidants in the literature, however the product selectivities do not exceed 50% due to formation of further oxidation products (In Supplemantary File) (Kowalski et al, 2003;Narayanan et al, 2002;Shimanskaya et al, 2014;Zalomaeva et al 2007;. In this study, selectivites reached to 60-65 % with 95-99 % conversions using novel nanomagnetite@SiO 2 ) (core@shell) supported aminomethylphosphine-Pd(II) complexes.…”

New routes to Vitamin K3

“…The development of cleaner, catalytic methods for the synthesis of menadione is therefore a challenging goal. Several catalytic procedures based on the oxidation of MN were reported (Table 1) [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. In general, the selectivity is moderate due to formation of numerous side-products (Scheme 2), the main one being isomeric 6-methyl-1,4-naphthoquinone (6-MNQ).…”