Iron Metabolism in Normal and Pathological Conditions

Abstract

Today, the development of medical science involves the constant improvement of the diagnosis of iron-deficiency conditions, which are extremely common among the population, and especially among women of reproductive age, pregnant women and children. According to the World Health Organization (WHO), about 500 million women in the world suffer from anemia, and 40-55% of women of reproductive age have latent iron deficiency. The problem of timely diagnosis of iron deficiency or excess in the body is extremely urgent and requires doctors to know the peculiarities of iron metabolism in normal conditions and in pathological conditions that can cause the development of serious complications.
 Is to generalize the diagnostic criteria for disorders of iron metabolism in accordance with the new knowledge of the homeostasis of this metabolite.
 Understanding the mechanisms of the physiology and pathophysiology of iron metabolism, the ability to correctly interpret the biochemical indicators characterizing the metabolic processes of this element in normal and pathological conditions will enable the clinician to timely diagnose iron metabolism disorders in the patient's body, especially at the preclinical stage, and take measures to prevent them, differentiate hypochromic anemias, choose adequate therapy and monitor its effectiveness.