2012
DOI: 10.1039/c2cc31045g
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Iron oxide-filled micelles as ligands for fac-[M(CO)3]+ (M = 99mTc, Re)

Abstract: Magnetite-filled micelles capture fac-[M(OH(2))(3)(CO)(3)](+) complexes (M = (99m)Tc, Re), creating versatile self-assembled constructs for multimodal SPECT/MR/optical imaging and radiopharmaceutical guided delivery.

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Cited by 13 publications
(10 citation statements)
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“…mSPION, mSPION-OVA and rhodamine-labelled micelles were prepared as described previously. [58,70,118] For the synthesis of mZnSPION, different ZnSPION-to-lipid ratios were used to optimize the micelling process and the properties (e.g. size).…”
Section: Synthesis and Characterization Of Mznspion(-polyic-r837) And Mspion(-ova)mentioning
confidence: 99%
“…mSPION, mSPION-OVA and rhodamine-labelled micelles were prepared as described previously. [58,70,118] For the synthesis of mZnSPION, different ZnSPION-to-lipid ratios were used to optimize the micelling process and the properties (e.g. size).…”
Section: Synthesis and Characterization Of Mznspion(-polyic-r837) And Mspion(-ova)mentioning
confidence: 99%
“…Recently, we found that this 99m Tc tricarbonyl complex binds to the surface of magnetic nanoparticles (MNPs) providing MRI-SPECT dual modality imaging. 20 Considering that sulphur containing ligands show strong affinity for metal(I) carbonyl centers, we wondered if the sulphur rich surface of the QDs could serve as a ligand for the [ 99m Tc(CO) 3 ] + moiety to provide SPECT imaging capabilities in the MQDs. Indeed, the preformed MQDs readily captured the 99m Tc tricarbonyl complex after 30 min reaction at 90 1C with high radiolabelling yields (up to 89%).…”
mentioning
confidence: 99%
“…Hydrophobic iron oxide nanoparticles were synthetized following previously described method (Sun et al, 2004;Gomez Blanco et al, 2012). The IONP-filled micelles (mIONPs) were produced by self-assembly using a dry-film hydration method (Carion et al, 2007).…”
Section: Synthesis and Characterisation Of Nanovaccinesmentioning
confidence: 99%