Iron-related parameters in Spanish mares during pregnancy

Montesinos, P.; Satué, K.

doi:10.1007/s00580-011-1364-7

Cited by 6 publications

(1 citation statement)

References 45 publications

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“…Although several studies on Quarter Horse, Thoroughbred (Harvey et al, 1994;Faramarzi et al, 2018), Marchador Mangalarga (Silva et al, 2019), Standardbred (Mariella et al, 2014), and Andalusian mares (Faramarzi et al, 2018) have reported decreased erythrocyte parameters, in Carthusian pregnant mares (Satué et al, 2009) no changes have been revealed during gestation. Despite the existing information about the hematological variables, the parameters indicative of the iron status are very scarce and fragmentary, having detected increases in Fe and Ferr in pregnant (Montesinos and Satué, 2013) and in HB and Fe in peripartum mares (Fazio et al, 2019). What is more, the existence of estrogen-iron axes in both pregnant and cyclic mares was recently recorded (Satuè et al, 2023a, b) along with related changes in hepcidin, ferritin, and iron homeostasis (Satue et al, 2023c, d).…”

Section: Introductionmentioning

confidence: 99%

Hematological indexes and iron status in pregnant mares

2023

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Abstract. During pregnancy, iron requirements are increased to meet optimal placental and fetal growth and the expansion of the maternal red-cell mass and to prevent complications related to the mother's iron deficiency anemia. Red-cell parameters and iron status provide consistent additional information for diagnosis of iron deficiency conditions. The aim of this study was to evaluate the serum iron status and its relation to hematological indexes in pregnant mares. Blood samples were taken from 31 Spanish Purebred mares over 11 months of pregnancy. Concentrations of iron (Fe), ferritin (Ferr), transferrin (T), and total iron-binding capacity (TIBC) increased significantly and unsaturated iron-binding capacity (UIBC) decreased as the pregnancy progressed without changes in red blood cell (RBC) count, hemoglobin (HB) concentration, packed cell volume (PCV), and transferrin saturation (TSAT). Fe and Ferr were positively correlated (r=0.21). Fe and T (r=0.69) and Fe and TSAT (r=0.94) were positively correlated, and Fe and UIBC were negatively correlated (r=-0.69). T and TIBC were positively correlated (r=1.00). Pregnancy in the Spanish Purebred mare is characterized by a progressive increase in Fe, Ferr, T, and TIBC and a decrease in UIBC without modification in hematological indexes. Hematological parameters and iron status seem to indicate a sufficiency for Fe transport and its related mobilization and utilization during gestation in Spanish Purebred mares.

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