Irradiation of localized prostatic carcinoma with a combination of high dose rate iridium-192 brachytherapy and external beam radiotherapy with three target definitions and dose levels inside the prostate gland

High-Dose Rate Brachytherapy of Prostatic Adenocarcinoma in Combination with External Beam Radiotherapy

“…During 1988 to 1995 a total number of 50 were treated. The initial results, short followup, from the first 50 patients have been reported previously [4]. In this paper we report the results after an average of 6 years after treatment.…”

3D Interstitial HDR Brachytherapy Combined with 3D External Beam Radiotherapy and Androgen Deprivation for Prostate Cancer Preliminary Results

“…Kovacs et al [14] reported in a large series of 171 patients an excellent local control rate of 89% for T1/T2 and 85% for T3 Stages using 2 HDR brachytherapy fractions of each 15 Gy combined with 50 Gy of EBRT. Borghede et al [7] and Dinges et al [9] reported promising preliminary results of transperineal HDR brachytherapy combined with EBRT. Borghede et al Based on these experiences and encouraged by these results we have created and introduced a new technique of implantation and treatment planning for HDR brachytherapy of prostate cancer.…”

Clinical outcome in patients with prostate cancer treated with external beam radiotherapy and high dose-rate iridium 192 brachytherapy boost: A 6-year follow-up

“…The technique has previously been described in detail [2]. In general 10 Á18 needles were used, and the duration of the procedure was usually 2 hours in total.…”

“…The principle of this treatment has been reported previously [2]. This combination delivers a normalized dose equivalent of 2 Gy per fraction (NTD) of more than 104 Gy (assuming a conservative tumour alpha/beta ratio 0/3 Gy).…”